Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The biocompatibility of scaffolds for orthopaedic tissue engineering using enhanced green fluorescent protein (EGFP)-labeled human bone marrow fibroblastic (HBMF) stem cells was evaluated. The cells were examined by light and fluorescence microscopy after culture for up to 21 days in vitro and then implanted subcutaneously into severe combined immunodeficient/non-obese diabetic mice. The results show that after 21 days in vitro, EGFP-cells could readily be detected by their green fluorescence under incident fluorescence microscopy. It was found that the use of RGFP-labelled HBMF cells is an effective tool to evaluate the interactions between the cells and biomaterials both in vivo and vitro.


Conference paper

Publication Date