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Inflammatory insults affect platelet production, but it is yet unknown what mechanisms can drive rapid adaptations in thrombopoiesis. In this issue of Immunity, Petzold et al. (2022) propose that neutrophils "pluck" on megakaryocytes in the bone marrow to tune platelet release.

Original publication

DOI

10.1016/j.immuni.2022.11.012

Type

Journal article

Journal

Immunity

Publication Date

13/12/2022

Volume

55

Pages

2217 - 2219

Keywords

Blood Platelets, Neutrophils, Thrombopoiesis, Megakaryocytes, Bone Marrow