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UNLABELLED: This paper provides a framework for the development of national guidelines for the management of glucocorticoid-induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer. INTRODUCTION: The need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. METHODS AND RESULTS: The epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review. CONCLUSIONS: Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of each country.

Original publication

DOI

10.1007/s00198-012-1958-1

Type

Journal article

Journal

Osteoporos int

Publication Date

09/2012

Volume

23

Pages

2257 - 2276

Keywords

Aged, Aged, 80 and over, Bone Density, Bone Density Conservation Agents, Female, Glucocorticoids, Humans, Male, Middle Aged, Osteoporosis, Practice Guidelines as Topic, Risk Assessment, Risk Factors, Treatment Outcome