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The properties of three I region associated immunoregulatory factors involved in cell interactions are described. These are antigen specific T helper factor, suppressor factor produced by metabolically active T cells and genetically restricted factor, which is produced by macrophages and is involved in T helper cell induction. The use of these factors to analyse cell interactions is discussed.

Type

Journal article

Journal

Advances in experimental medicine and biology

Publication Date

01/1978

Volume

98

Pages

325 - 338

Keywords

Lymphocytes, Macrophages, Animals, Mice, Peptides, Immunosuppression, Lymphocyte Cooperation, Antibody Formation, Immunity, Cellular, Genes, MHC Class II