Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The present review attempts to reconcile the dichotomy that exists in the literature in relation to fibromyalgia, in that it is considered either a somatic response to psychological stress or a distinct organically based syndrome. Specifically, the hypothesis explored is that the link between chronic stress and the subsequent development of fibromyalgia can be explained by one or more abnormalities in neuroendocrine function. There are several such abnormalities recognised that both occur as a result of chronic stress and are observed in fibromyalgia. Whether such abnormalities have an aetiologic role remains uncertain but should be testable by well-designed prospective studies.

Original publication

DOI

10.1186/ar1176

Type

Journal article

Journal

Arthritis research & therapy

Publication Date

01/2004

Volume

6

Pages

98 - 106

Addresses

ARC Epidemiology Unit, School of Epidemiology and Health Sciences, Manchester, UK. anindya.gupta@man.ac.uk

Keywords

Neurosecretory Systems, Animals, Humans, Fibromyalgia, Stress, Psychological