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Publications

Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.

Thompson KN. et al, (2023), Sci transl med, 15

MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses.

Heuberger CE. et al, (2023), Mucosal immunol

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.

Hackstein C-P. et al, (2022), Nat commun, 13

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.

Ryzhakov G. et al, (2021), Nat commun, 12

Accurate identification and quantification of commensal microbiota bound by host immunoglobulins.

Jackson MA. et al, (2021), Microbiome, 9

Mucosal immune responses in COVID19 - a living review.

Pearson CF. et al, (2021), Oxf open immunol, 2

Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life.

Verheijen M. et al, (2020), Cell rep, 33

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory.

Hogan T. et al, (2019), Elife, 8

IgA-coated commensal gut bacteria drive local and joint pathology in inflammatory arthritis.

LAM L. et al, (2019)

IgG-coating reveals maladapted interactions of a pre-colitic microbiome.

LAM L. et al, (2019)

Longitudinal metatranscriptomics reveals bacterial functions promoting gastrointestinal inflammation.

JACKSON M. et al, (2019)

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.

Ryzhakov G. et al, (2018), Nat commun, 9

Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice.

Meinicke H. et al, (2017), Immunology, 152, 74 - 88

T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine.

Krausgruber T. et al, (2016), Nat commun, 7

The autophagy gene Atg16I1 differentially regulates T-reg and T(H)2 cells to control intestinal inflammation

Kabat AM. et al, (2016), Elife, 5

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.

Kabat AM. et al, (2016), Elife, 5

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.

Pearson C. et al, (2016), Elife, 5

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis.

Griseri T. et al, (2015), Immunity, 43, 187 - 199

Innate lymphoid cells in models of IBD

Pearson C. et al, (2012), Immunology, 137, 222 - 223

Lymphoid microenvironments and innate lymphoid cells in the gut.

Pearson C. et al, (2012), Trends immunol, 33, 289 - 296

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