Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Journal article
Thompson KN. et al, (2023), Sci transl med, 15
MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses.
Journal article
Heuberger CE. et al, (2023), Mucosal immunol
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.
Journal article
Hackstein C-P. et al, (2022), Nat commun, 13
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
Journal article
Ryzhakov G. et al, (2021), Nat commun, 12
Accurate identification and quantification of commensal microbiota bound by host immunoglobulins.
Journal article
Jackson MA. et al, (2021), Microbiome, 9
Mucosal immune responses in COVID19 - a living review.
Journal article
Pearson CF. et al, (2021), Oxf open immunol, 2
Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life.
Journal article
Verheijen M. et al, (2020), Cell rep, 33
Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory.
Journal article
Hogan T. et al, (2019), Elife, 8
IgA-coated commensal gut bacteria drive local and joint pathology in inflammatory arthritis.
Working paper
LAM L. et al, (2019)
IgG-coating reveals maladapted interactions of a pre-colitic microbiome.
Working paper
LAM L. et al, (2019)
Longitudinal metatranscriptomics reveals bacterial functions promoting gastrointestinal inflammation.
Working paper
JACKSON M. et al, (2019)
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.
Journal article
Ryzhakov G. et al, (2018), Nat commun, 9
Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice.
Journal article
Meinicke H. et al, (2017), Immunology, 152, 74 - 88
T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine.
Journal article
Krausgruber T. et al, (2016), Nat commun, 7
The autophagy gene Atg16I1 differentially regulates T-reg and T(H)2 cells to control intestinal inflammation
Journal article
Kabat AM. et al, (2016), Elife, 5
The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Journal article
Kabat AM. et al, (2016), Elife, 5
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
Journal article
Pearson C. et al, (2016), Elife, 5
Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis.
Journal article
Griseri T. et al, (2015), Immunity, 43, 187 - 199
Innate lymphoid cells in models of IBD
Conference paper
Pearson C. et al, (2012), Immunology, 137, 222 - 223
Lymphoid microenvironments and innate lymphoid cells in the gut.
Journal article
Pearson C. et al, (2012), Trends immunol, 33, 289 - 296