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Publications

Current usage of explainer animations in trials: a survey of the UKCRC registered clinical trial units in the UK.

Barber VS. et al, (2024), Trials, 25

Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases.

Kawano-Dourado L. et al, (2024), Thorax

Ivermectin for COVID-19 in adults in the community (PRINCIPLE): an open, randomised, controlled, adaptive platform trial of short- and longer-term outcomes.

Hayward G. et al, (2024), J infect

Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients

Standing JF. et al, (2024), Nature communications, 15

Time to speed up scientific deliveries in fibrotic interstitial lung disease: Innovative clinical trial design to improve patient care

RICHARDS D., (2024), Thorax

Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in the UK PANORAMIC trial.

Png ME. et al, (2024), Br j gen pract

Use of oxygen-loaded nanobubbles to improve tissue oxygenation: Bone-relevant mechanisms of action and effects on osteoclast differentiation.

Knowles HJ. et al, (2023), Biomaterials, 305

Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.

Weeratunga P. et al, (2023), Nat commun, 14

Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS-CoV-2.

Higham HE. et al, (2023), Br j clin pharmacol

Optimising Psoriatic Arthritis Therapy with Immunological Methods to Increase Standard Evaluation: The protocol of an open-label multi-centre, parallel-group, two arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis.

RICHARDS D., (2023), Bmj open

Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease.

Gbinigie O. et al, (2023), Bmj open, 13

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.

Butler CC. et al, (2022), Lancet

An observational, non-interventional study for the follow-up of patients with amyloidosis who received miridesap followed by dezamizumab in a phase 1 study

Richards D. et al, (2022), Orphanet journal of rare diseases, 17

In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review.

Drennan PG. et al, (2022), Clin transl sci

In vivo human keyhole limpet haemocyanin challenge in early phase drug development: A systematic review

Drennan P. et al, (2022), Clinical and translational science

Molnupiravir Plus Usual Care Versus Usual Care Alone as Early Treatment for Adults with COVID-19 at Increased Risk of Adverse Outcomes (PANORAMIC): Preliminary Analysis from the United Kingdom Randomised, Controlled Open-Label, Platform Adaptive Trial

Butler C. et al, (2022)

Predictive validity in drug discovery: what it is, why it matters and how to improve it

RICHARDS D., (2022), Nature reviews drug discovery

Corrigendum to 'Multiple endocrine neoplasia type 1 in children and adolescents: Clinical features and treatment outcomes' [Surgery 171 (2021) 77-87].

Shariq OA. et al, (2022), Surgery

COVID-19 therapeutics: challenges and directions for the future

Robinson PC. et al, (2022), Proceedings of the national academy of sciences

Colchicine for COVID-19 in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial.

Dorward J. et al, (2022), Br j gen pract

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