Use of oxygen-loaded nanobubbles to improve tissue oxygenation: Bone-relevant mechanisms of action and effects on osteoclast differentiation.
Knowles HJ. et al, (2024), Biomaterials, 305
Editorial: Advances in the endocrine role of the skeleton volume II.
Rossi M. et al, (2023), Front endocrinol (lausanne), 14
Mature primary human osteocytes in mini organotypic cultures secrete FGF23 and PTH1-34-regulated sclerostin.
Knowles HJ. et al, (2023), Front endocrinol (lausanne), 14
A New Method to Sort Differentiating Osteoclasts into Defined Homogeneous Subgroups.
Hulley PA. and Knowles HJ., (2022), Cells, 11
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cottone L. et al, (2022), Cell death differ
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone
Cottone L. et al, (2022), Journal of bone and mineral research, 37, 98 - 98
Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs.
Larrouture QC. et al, (2021), Sci rep, 11
Hypoxia-inducible factor (HIF)-mediated effects of the hypoxic niche in bone cancer
Knowles HJ., (2021), Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, 321 - 335
Distinct roles for the hypoxia-inducible transcription factors HIF-1alpha and HIF-2alpha in human osteoclast formation and function
Knowles H., (2020), Scientific reports
Osteoblast-Osteoclast Coculture Amplifies Inhibitory Effects of FG-4592 on Human Osteoclastogenesis and Reduces Bone Resorption.
Hulley PA. et al, (2020), Jbmr plus, 4
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.
Gooding S. et al, (2019), Nat commun, 10
The Adenosine A2B Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments.
Knowles HJ., (2019), Cells, 8
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
Larrouture Q. et al, (2019), Journal of bone and mineral research, 34, 235 - 235
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
Larrouture QC. et al, (2018), Jbmr plus, 2, 17 - 18
Specific analysis of osteoclast-mediated bone resorption by differentiation of primary human osteoclasts in 3D
KNOWLES H. and Papadimitriou-Olivgeri I., (2018)
BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.
Ngeow KC. et al, (2018), Proc natl acad sci u s a, 115, E8668 - E8677
Angiopoietin-like 4 promotes osteosarcoma cell proliferation and migration and stimulates osteoclastogenesis.
Zhang T. et al, (2018), Bmc cancer, 18