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Publications

ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells.

Carretero-Iglesia L. et al, (2024), Nat cancer

Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma.

Grandclément C. et al, (2024), Nat commun, 15

Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.

Pouleau B. et al, (2023), Blood, 142, 260 - 273

Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival.

Whitburn J. et al, (2022), Sci adv, 8

EphA2 Is a Clinically Relevant Target for Breast Cancer Bone Metastatic Disease

Vaught DB. et al, (2021), Jbmr plus

Biodegradable Magnesium Alloys Promote Angio-Osteogenesis to Enhance Bone Repair

Han H-S. et al, (2020), Advanced science

Modeling the Human Bone-Tumor Niche: Reducing and Replacing the Need for Animal Data.

Rao SR. et al, (2020), Jbmr plus, 4

Dysregulated Adiponectin Signalling via AdipoR1 Deletion Leads to Bone Loss and Increased Marrow Adiposity In Vivo Through Distinct Local and Systemic Mechanisms and in Contrast to Epidemiological Evidence

Sowman A. et al, (2019), Journal of bone and mineral research, 34, 77 - 77

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.

Gooding S. et al, (2019), Nat commun, 10

Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment.

Olechnowicz SWZ. et al, (2019), Sci rep, 9

Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp).

Rao SR. et al, (2019), Sci rep, 9

Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300: response to correspondence by Borzì et al.

Sacitharan PK. et al, (2019), Exp mol med, 51

Dysregulated Adiponectin Signalling via AdipoR1 Deletion Leads to Bone Loss and Increased Marrow Adiposity In Vivo Through Distinct Local and Systemic Mechanisms and in Contrast to Epidemiological Evidence

Sowman A. et al, (2019), Journal of bone and mineral research, 34, 77 - 77

A new corrosion-inhibiting strategy for biodegradable magnesium: reduced nicotinamide adenine dinucleotide (NADH).

Park J. et al, (2018), Sci rep, 8

The polyphenol resveratrol promotes skeletal growth in mice through a sirtuin 1-bone morphogenic protein 2 longevity axis.

Zhao M. et al, (2018), Br j pharmacol, 175, 4183 - 4192

Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300.

Sacitharan PK. et al, (2018), Exp mol med, 50

Transgenic zebrafish model for quantification and visualization of tissue toxicity caused by alloying elements in newly developed biodegradable metal.

Han H-S. et al, (2018), Sci rep, 8

Corrosion behavior of biodegradable Mg-based alloys via femtosecond laser surface melting

(2018), Applied surface science

Current status and outlook on the clinical translation of biodegradable metals

Han H. et al, (2018), Materials today

Effect of spatial arrangement and structure of hierarchically patterned fibrous scaffolds generated by a femtosecond laser on cardiomyoblast behavior.

Jun I. et al, (2018), J biomed mater res a, 106, 1732 - 1742

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