Does decorin stabilize the extracellular matrix of articular cartilage and slow the progression of osteoarthritis?
Journal article
Saklatvala J., (2021), Osteoarthritis cartilage, 29, 1094 - 1095
Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis.
Journal article
Gardiner MD. et al, (2015), Osteoarthritis cartilage, 23, 616 - 628
Generation of a mouse line harboring a Bi-transgene expressing luciferase and tamoxifen-activatable creER(T2) recombinase in cartilage.
Journal article
Lo Cascio L. et al, (2014), Genesis, 52, 110 - 119
Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivo.
Journal article
Chong K-W. et al, (2013), Arthritis rheum, 65, 2346 - 2355
Interleukin 1 induces aggrecan degradation by human articular chondrocytes through a TAK1/MKK4/JNK2 pathway without involvement of NFKB
Conference paper
Ismail HM. et al, (2013), Osteoarthritis and cartilage, 21, S127 - S127
Identifying synovial tissue-derived catabolic factors of cartilage aggrecan
Conference paper
Rana F. et al, (2013), International journal of experimental pathology, 94, A38 - A38
Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage.
Journal article
Watt FE. et al, (2013), Arthritis rheum, 65, 397 - 407
Heat shock protein B1-deficient mice display impaired wound healing.
Journal article
Crowe J. et al, (2013), Plos one, 8
Generation of an inducible cartilage-specific deleter using human aggrecan enhancer/promoter that is trackable in vivo using luciferase
Conference paper
Lo Cascio L. et al, (2012), Glycobiology, 22, 1576 - 1576
Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo.
Journal article
Burleigh A. et al, (2012), Arthritis rheum, 64, 2278 - 2288
Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.
Journal article
Joanny E. et al, (2012), Br j pharmacol, 165, 1124 - 1136
Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.
Journal article
Buss H. et al, (2012), Plos one, 7
Pathogenic protease expression in murine OA is critically dependent upon mechanical joint loading
Conference paper
Burleigh A. et al, (2012), Arthritis research & therapy, 14
The dependence of FGF2 on murine cartilage injury responses
Conference paper
Chong KW. et al, (2011), International journal of experimental pathology, 92, A23 - A24
Cyclic mechanical load causes global translational arrest in articular chondrocytes: a process which is partially dependent upon PKR phosphorylation.
Journal article
Lomas C. et al, (2011), Eur cell mater, 22, 178 - 189
039 PARTIAL JOINT IMMOBILISATION PROTECTS AGAINST OA AND REVEALS DISTINCT BIOMECHANICAL THRESHOLDS IN THE JOINT
Conference paper
Burleigh A. et al, (2010), Osteoarthritis and cartilage, 18, S25 - S25
MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment.
Journal article
Marchese FP. et al, (2010), J biol chem, 285, 27590 - 27600
Concurrent Oral 11 - Osteoarthritis [OP73-OP78]: OP73. Mechanical Load Drives Inflammatory Gene Expression and Disease in Murine OA
Conference paper
Burleigh A. et al, (2010), Rheumatology, 49, i32 - i34
Connective tissue growth factor: matrix localisation, regulation and possible function in articular cartilage
Conference paper
McLean C. et al, (2010), International journal of experimental pathology, 91, A24 - A24
Structural and regulatory components of the pericellular matrix of young and mature articular cartilage
Conference paper
McLean C. et al, (2010), International journal of experimental pathology, 91, A23 - A23