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25 years of biologic DMARDs in rheumatology.

Journal article

Feldmann M. et al, (2023), Nat rev rheumatol

Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300.

Journal article

Williams LM. et al, (2020), Proc natl acad sci u s a, 117, 20753 - 20763

Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed.

Journal article

Feldmann M. et al, (2020), Lancet, 395, 1407 - 1409

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.

Journal article

Cribbs AP. et al, (2020), Proc natl acad sci u s a, 117, 6056 - 6066

TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells.

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Tseng W-Y. et al, (2019), Proc natl acad sci u s a, 116, 21666 - 21672

Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to GAlert.

Journal article

Lee G. et al, (2018), Proc natl acad sci u s a, 115, E4463 - E4472

Developments in therapy with monoclonal antibodies and related proteins.

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Shepard HM. et al, (2017), Clin med (lond), 17, 220 - 232

Anti-TNF Therapy.

Journal article

Udalova I. et al, (2016), Microbiol spectr, 4

Macrophage heterogeneity in the context of rheumatoid arthritis.

Journal article

Udalova IA. et al, (2016), Nat rev rheumatol, 12, 472 - 485

Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development.

Journal article

Cole JE. et al, (2015), Proc natl acad sci u s a, 112, 13033 - 13038

Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications.

Journal article

Cribbs A. et al, (2015), Ther adv musculoskelet dis, 7, 206 - 219

Selective inhibition of TNFR1 reduces osteoclast numbers and is differentiated from anti-TNF in a LPS-driven model of inflammatory bone loss.

Journal article

Espirito Santo AI. et al, (2015), Biochem biophys res commun, 464, 1145 - 1150

IRF5 controls both acute and chronic inflammation

Journal article

Weiss M. et al, (2015), Proceedings of the national academy of sciences of the united states of america, 112, 11001 - 11006

IRF5 controls both acute and chronic inflammation.

Journal article

Weiss M. et al, (2015), Proc natl acad sci u s a, 112, 11001 - 11006

Perspectives From Masters in Rheumatology and Autoimmunity: Can We Get Closer to a Cure for Rheumatoid Arthritis?

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Feldmann M. and Maini RN., (2015), Arthritis rheumatol, 67, 2283 - 2291

Preclinical target validation using patient-derived cells.

Journal article

Edwards AM. et al, (2015), Nat rev drug discov, 14, 149 - 150

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