Anushka Soni
MA BMBCh MRCP DPhil
Clinical Research Fellow
Mechanisms of pain in arthritis
Research
I am a Rheumatologist with a research interest in musculoskeletal pain mechanisms. During my DPhil, I studied the impact of abnormal central pain processing in patients with osteoarthritis of the knee. I showed a relationship between the presence of neuropathic pain and central sensitization pre-operatively, and that this modified the patient’s response to knee replacement surgery. Moving forwards, my work will use a combination of techniques, including neuroimaging and clinical pain quantification, to investigate pain related predictors of response to treatment in inflammatory arthritis.
Background
I completed my medical degree at Magdalen College, Oxford in 2003 having obtained a BA Hons (Cantab) in Natural Sciences in 2000. I then completed my general medical training at the Oxford Deanery and moved to the North London Deanery in 2007 to commence my specialist training in Rheumatology. I returned to the Oxford Deanery in 2008 and took up a Clinical lecturer post in 2009. During my specialist training I secured an NIHR Doctoral Research Fellowship in order to complete a DPhil (Oxon) entitled “Pain Characterisation in Osteoarthritis”. I have now completed my specialist training in Rheumatology and have been awarded a four-year Oxford-UCB Prize fellowship, which I started in September 2017, to advance and translate my work on pain mechanisms to inflammatory arthritis.
Recent publications
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Hypothetical model ignores many important pathophysiologic mechanisms in fibromyalgia.
Journal article
Clauw DJ. et al, (2023), Nat rev rheumatol
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The natural history of chronic widespread pain in patients with axial spondyloarthritis: a cohort study with clinical and self-tracking data.
Journal article
Soni A. et al, (2022), Rheumatology (oxford)
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Progression of chronic pain and associated health-related quality of life and healthcare resource use over 5 years after total knee replacement: evidence from a cohort study.
Journal article
Cole S. et al, (2022), Bmj open, 12
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HOSPITALISATION IN FIBROMYALGIA: A COHORT-LEVEL OBSERVATIONAL STUDY OF IN-PATIENT PROCEDURES, COSTS AND GEOGRAPHICAL VARIATION IN ENGLAND.
Journal article
SONI A. et al, (2019), Rheumatology
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Central Sensitization in Knee Osteoarthritis: Relating Presurgical Brainstem Neuroimaging and PainDETECT-Based Patient Stratification to Arthroplasty Outcome.
Journal article
Soni A. et al, (2019), Arthritis rheumatol, 71, 550 - 560