Anushka Soni
MA BMBCh MRCP DPhil
Clinical Research Fellow
Mechanisms of pain in arthritis
Research
I am a Rheumatologist with a research interest in musculoskeletal pain mechanisms. During my DPhil, I studied the impact of abnormal central pain processing in patients with osteoarthritis of the knee. I showed a relationship between the presence of neuropathic pain and central sensitization pre-operatively, and that this modified the patient’s response to knee replacement surgery. Moving forwards, my work will use a combination of techniques, including neuroimaging and clinical pain quantification, to investigate pain related predictors of response to treatment in inflammatory arthritis.
Background
I completed my medical degree at Magdalen College, Oxford in 2003 having obtained a BA Hons (Cantab) in Natural Sciences in 2000. I then completed my general medical training at the Oxford Deanery and moved to the North London Deanery in 2007 to commence my specialist training in Rheumatology. I returned to the Oxford Deanery in 2008 and took up a Clinical lecturer post in 2009. During my specialist training I secured an NIHR Doctoral Research Fellowship in order to complete a DPhil (Oxon) entitled “Pain Characterisation in Osteoarthritis”. I have now completed my specialist training in Rheumatology and have been awarded a four-year Oxford-UCB Prize fellowship, which I started in September 2017, to advance and translate my work on pain mechanisms to inflammatory arthritis.
Recent publications
Why sleep matters in chronic pain: evidence across the lifespan.
Journal article
Kelleher EM. et al, (2026), EBioMedicine
Exploring the effects of GLP-1 receptor agonists in fibromyalgia: a propensity-matched real-world cohort using the TriNetX research platform.
Journal article
Eshak N. et al, (2026), Rheumatology (Oxford), 65
Pharmacoepidemiologic characterization of cannabis use and symptomatology in rheumatology using natural language processing of electronic health record clinic notes.
Journal article
Falasinnu T. et al, (2026), J Pain, 39
ddressing the unmet challenge of pain in rare bone diseases: new insights from the RUDY UK registry.
Journal article
Legrand MA. et al, (2026), Orphanet J Rare Dis, 21
Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis.
Journal article
Kelleher EM. et al, (2026), Arthritis Care Res (Hoboken), 78, 3 - 14