Research groups
Collaborators
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Sarah Snelling
Associate Professor
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Christopher Buckley
Kennedy Professor of Translational Rheumatology and Director of Clinical Research
Jolet Mimpen
DPhil, MSc, BSc (Hons)
Postdoctoral Research Fellow
Jolet obtained her BSc (Hons) in Pharmaceutical Sciences from Utrecht University (the Netherlands), before moving to Oxford in 2015 for the MSc in Pharmacology. She then moved to the Botnar Research Centre in 2016 to read for a DPhil in Cellular and Molecular Medicine at NDORMS under the supervision of Prof. Andrew Carr, Assoc. Prof. Sarah Snelling, and Assoc. Prof. Stephanie Dakin. She worked on the project entitled “Inflammation in osteoarthritis – a focus on interleukin-17”, which she successfully defended in January 2020.
From January 2020 until May 2022, Jolet worked as a postdoctoral researcher on the CZI-funded "Tendon Seed Network" project, which is part of the Human Cell Atlas. The Tendon Seed Network project aims to spatially define the transcriptome of healthy tendon, an extracellular matrix-rich tissue, across multiple anatomic and micro-anatomic sites. To enable this, her work focussed on the development and execution of laboratory protocols for single nucleus RNA Sequencing of tendons.
In 2022, Jolet was awarded a Versus Arthritis Foundation Fellowship to study inflammation and fibrosis in osteoarthritis synovium with Prof Christopher Buckley and Prof Sarah Snelling.
Recent publications
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Single nucleus and spatial transcriptomic profiling of human healthy hamstring tendon
Preprint
Mimpen JY. et al, (2022)
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Humanoid robots to mechanically stress human cells grown in soft bioreactors
Journal article
Mouthuy P-A. et al, (2022), Communications engineering, 1
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Adaption for small samples - Nuclei isolation from snap-frozen tissue for single nucleus RNA Sequencing v1
Preprint
Y Mimpen J. et al, (2022)
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Adaption for small samples - Nuclei isolation from snap-frozen tissue for single nucleus RNA Sequencing v1
Preprint
Y Mimpen J. et al, (2022)
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SOP for snap-freezing tissues v1
Preprint
Y Mimpen J. et al, (2021)