Research groups
Collaborators
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Sarah Snelling
Professor of Musculoskeletal Science
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Christopher Buckley
Kennedy Professor of Translational Rheumatology and Director of Clinical Research
Jolet Mimpen
DPhil, MSc, BSc (Hons)
Senior Research Fellow in Musculoskeletal Tissue Biology
- Arthritis UK Bridging Fellow
Jolet is an Arthritis UK Fellow with an interest in musculoskeletal tissue biology. Jolet leads and collaborates on different projects on osteoarthritis which aim to characterise soft joint tissues to improve our understanding of their role in this disease.
As part of Sarah Snelling’s team, Jolet has been involved in several projects that aim to characterise musculoskeletal tissues in health and disease, including tendons and ligaments. Specifically, she has developed and executed several laboratory methods for single nucleus RNA sequencing of soft musculoskeletal tissues for atlassing efforts that are part of the Human Cell Atlas initiative.
Jolet’s background includes degrees in Pharmaceutical Sciences (BSc (Hons), Utrecht University), Pharmacology (MSc, University of Oxford), and Molecular and Cellular Medicine (DPhil, University of Oxford). Throughout her degrees and postdoctoral project, she has focussed on understanding inflammatory and fibrotic mechanisms in soft tissues.
Recent publications
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Cellular and molecular landscapes of human tendons across the lifespan revealed by spatial and single-cell transcriptomics
Preprint
Kurjan A. et al, (2025)
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Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution.
Journal article
Mimpen JY. et al, (2025), J physiol
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Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review.
Journal article
Raza IGA. et al, (2024), Bone joint res, 13, 703 - 715
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Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution
Preprint
Mimpen J. et al, (2024)
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Single nucleus and spatial transcriptomic profiling of healthy human hamstring tendon.
Journal article
Mimpen JY. et al, (2024), Faseb j, 38