Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Kalle Soderstrom

MSc, PhD

Honorary Departmental Senior Research Fellow.

We study the role of Natural Killer (NK) cells and other innate lymphoid cells (iLC) in chronic inflammatory diseases mainly rheumatoid arthritis (RA). We focus our studies on the development and function of tissue localized NK cells and here use epigenetic tools to decipher regulatory elements involved in NK cell subset differentiation and functional specialization within the tissue environment.

We are particularly focusing on the functional capacity of NK cells and other innate lymphoid cells to drive downstream disease relevant inflammatory pathways such as myeloid cell differentiation and activation, dendritic cell (DC) differentiation, osteoclastogenesis, and stromal cell activation.

We aim to find novel means to target such pro-inflammatory pathways using antibodies, peptides, and small molecule epigenetic inhibitors