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Kalle Soderstrom

MSc, PhD

Honorary Departmental Senior Research Fellow.

We study the role of Natural Killer (NK) cells and other innate lymphoid cells (iLC) in chronic inflammatory diseases mainly rheumatoid arthritis (RA). We focus our studies on the development and function of tissue localized NK cells and here use epigenetic tools to decipher regulatory elements involved in NK cell subset differentiation and functional specialization within the tissue environment.

We are particularly focusing on the functional capacity of NK cells and other innate lymphoid cells to drive downstream disease relevant inflammatory pathways such as myeloid cell differentiation and activation, dendritic cell (DC) differentiation, osteoclastogenesis, and stromal cell activation.

We aim to find novel means to target such pro-inflammatory pathways using antibodies, peptides, and small molecule epigenetic inhibitors 

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Recent Publications

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