Contact information
Loren Kell
DPhil (Oxon), BSc (Hons)
Postdoctoral Research Assistant in Molecular Medicine
I am a postdoctoral researcher at the Botnar Institute, supervised by Prof. Lynne Cox, Prof. Katja Simon, and Dr Ghada Alsaleh. I have investigated human immune system ageing during both my BSc Immunology and Infection at University College London and during my DPhil at Oxford. My doctoral and current research focus on interventions that rejuvenate immune responses in old age by their ability to modulate mTOR activity and DNA damage. I work both with primary human cells in vitro and with samples from human clinical trials testing anti-ageing interventions.
Key publications
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The central role of DNA damage in immunosenescence.
Kell L. et al, (2023), Front aging, 4
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AB0124 DIMETHYL FUMARATE MODULATES T CELL METABOLISM AND FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENT SAMPLES
Kell L. et al, (2023), Scientific abstracts, 1241.1 - 1241
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Disparity in peripheral and renal B-cell depletion with rituximab in systemic lupus erythematosus: an opportunity for obinutuzumab?
Reddy VR. et al, (2022), Rheumatology, 61, 2894 - 2904