Lynn Dustin

• Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons.

  Laidlaw SM. et al, (2017), Gastroenterology, 153, 566 - 578.e5

• Hepatitis C virus: life cycle in cells, infection and host response, and analysis of molecular markers influencing the outcome of infection and response to therapy.

  Dustin LB. et al, (2016), Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

• MAIT cells are activated during human viral infections.

  van Wilgenburg B. et al, (2016), Nature communications, 7

• Innate and Adaptive Immune Responses in Chronic HCV infection.

  Dustin LB., (2015), Current drug targets

• Editorial: Recent Advances in HBV and HCV Immunology.

  Dustin LB. and Trehanpati N., (2015), Frontiers in immunology, 6

• Immune control and failure in HCV infection--tipping the balance.

  Dustin LB. et al, (2014), Journal of leukocyte biology, 96, 535 - 548

• Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis.

  Zignego AL. et al, (2014), Genes and immunity, 15, 500 - 505

• CHARACTERIZATION OF PHENOTYPE AND IMMUNOGLOBULIN GENES OF AUTOREACTIVE B CELLS IN SJOGREN'S SYNDROME

  Efthimiou P. et al, (2014), ANNALS OF THE RHEUMATIC DISEASES, 73, 358 - 358

• Immune control of HCV infection

  Dustin LB., (2014), HCV Infection and Cryoglobulinemia, 21 - 36

• The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development.

  Cashman SB. et al, (2014), Frontiers in immunology, 5

• Selection of apoptotic cell specific human antibodies from adult bone marrow.

  Grönwall C. et al, (2014), PloS one, 9

• Interferon lambda: opportunities, risks, and uncertainties in the fight against HCV.

  Laidlaw SM. and Dustin LB., (2014), Frontiers in immunology, 5

• Genome-wide association study of hepatitis C virus-and cryoglobulin-related vasculitis

  Zignego AL. et al, (2014), Genes and Immunity, 15, 500 - 505

• Somatic hypermutations confer rheumatoid factor activity in hepatitis C virus-associated mixed cryoglobulinemia.

  Charles ED. et al, (2013), Arthritis and rheumatism, 65, 2430 - 2440

• Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1).

  Fuller MJ. et al, (2013), Proceedings of the National Academy of Sciences of the United States of America, 110, 15001 - 15006

• Efficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells.

  Saeed M. et al, (2012), Antimicrobial agents and chemotherapy, 56, 5365 - 5373

• Too low to measure, infectious nonetheless.

  Dustin LB., (2012), Blood, 119, 6181 - 6182

• Interferon α-stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1.

  Stegmann KA. et al, (2012), The Journal of infectious diseases, 205, 1351 - 1362

• Natural history, pathogenesis, and prevention of HCV infection

  Charles ED. et al, (2012), HCV Infection and Cryoglobulinemia, 9788847017054, 11 - 19

• Primary, post-primary and non-specific immunoglobulin M responses in HCV infection.

  Dustin LB. and Charles ED., (2012), Antiviral therapy, 17, 1449 - 1452

• Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.

  Marukian S. et al, (2011), Hepatology (Baltimore, Md.), 54, 1913 - 1923

• Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.

  Andrus L. et al, (2011), Hepatology (Baltimore, Md.), 54, 1901 - 1912

• HCV and Blood Cells: How Can We Distinguish Infection from Association?

  Dustin LB. and Rice CM., (2011), HCV Infection and Cryoglobulinemia, 55 - 62

• Response: proliferative versus functional anergy

  Charles ED. and Dustin LB., (2011), Blood, 118, 3442 - 3442

• Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset.

  Charles ED. et al, (2011), Blood, 117, 5425 - 5437

• Chemokine antagonism in chronic hepatitis C virus infection.

  Charles ED. and Dustin LB., (2011), The Journal of clinical investigation, 121, 25 - 27

• A flow cytometry-based strategy to identify and express IgM from VH1-69+ clonal peripheral B cells.

  Charles ED. et al, (2011), Journal of immunological methods, 363, 210 - 220

• Hepatitis C virus-induced cryoglobulinemia.

  Charles ED. and Dustin LB., (2009), Kidney international, 76, 818 - 824

• Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells.

  Marukian S. et al, (2008), Hepatology (Baltimore, Md.), 48, 1843 - 1850

• Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia.

  Charles ED. et al, (2008), Blood, 111, 1344 - 1356

• Hepatitis C virus and alanine aminotransferase kinetics following B-lymphocyte depletion with rituximab: evidence for a significant role of humoral immunity in the control of viremia in chronic HCV liver disease.

  Lake-Bakaar G. et al, (2007), Blood, 109, 845 - 846

• Flying under the radar: the immunobiology of hepatitis C.

  Dustin LB. and Rice CM., (2007), Annual review of immunology, 25, 71 - 99

• Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection.

  Romero AI. et al, (2006), The Journal of infectious diseases, 194, 895 - 903

• Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C.

  Butera D. et al, (2005), Blood, 106, 1175 - 1182

• Quasispecies heterogeneity within the E1/E2 region as a pretreatment variable during pegylated interferon therapy of chronic hepatitis C virus infection.

  Chambers TJ. et al, (2005), Journal of virology, 79, 3071 - 3083

• Reexamining the role of the humoral immune response in control of hepatitis C virus infection.

  Dustin LB., (2004), Hepatology (Baltimore, Md.), 40, 756 - 758

• Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner.

  McKeating JA. et al, (2004), Journal of virology, 78, 8496 - 8505

• Accumulation of B lymphocytes with a naive, resting phenotype in a subset of hepatitis C patients.

  Ni J. et al, (2003), Journal of immunology (Baltimore, Md. : 1950), 170, 3429 - 3439

• The immunological relay race: B cells take antigen by synapse.

  Dustin ML. and Dustin LB., (2001), Nature immunology, 2, 480 - 482

• Ratiometric analysis of calcium mobilization

  Dustin LB., (2000), Clinical and Applied Immunology Reviews, 1, 5 - 15

• Expression of dominant-negative src-homology domain 2-containing protein tyrosine phosphatase-1 results in increased Syk tyrosine kinase activity and B cell activation.

  Dustin LB. et al, (1999), Journal of immunology (Baltimore, Md. : 1950), 162, 2717 - 2724

• T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice.

  Nakayama K. et al, (1995), The Journal of experimental medicine, 182, 1101 - 1109

• Ly-6C is a marker of memory CD8+ T cells.

  Walunas TL. et al, (1995), Journal of immunology (Baltimore, Md. : 1950), 155, 1873 - 1883

• Antigen-driven differentiation of naive Ig-transgenic B cells in vitro.

  Dustin LB. et al, (1995), Journal of immunology (Baltimore, Md. : 1950), 154, 4936 - 4949

• Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction.

  Schönrich G. et al, (1993), Journal of immunology (Baltimore, Md. : 1950), 151, 4098 - 4105

• Docosahexaenoic acid, a constituent of rodent fetal serum and fish oil diets, inhibits acquisition of macrophage tumoricidal function.

  Dustin LB. et al, (1990), Journal of immunology (Baltimore, Md. : 1950), 144, 4888 - 4897

• Pregnancy as a natural model of allograft tolerance. Interactions between adherent macrophages and trophoblast populations.

  Lu CY. et al, (1989), Transplantation, 48, 848 - 855

• High strength binding of P815 mastocytoma cells is not necessary for their lysis by macrophages which have been primed and triggered in vitro.

  Lu CY. et al, (1988), Journal of immunology (Baltimore, Md. : 1950), 141, 1083 - 1090

• Resolution of the phosphotransferase enzymes of Streptococcus mutans: purification and preliminary characterization of a heat-stable phosphocarrier protein.

  Mimura CS. et al, (1984), Infection and immunity, 44, 708 - 715

Recent Publications

• Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons.

  Laidlaw SM. et al, (2017), Gastroenterology, 153, 566 - 578.e5

• Hepatitis C virus: life cycle in cells, infection and host response, and analysis of molecular markers influencing the outcome of infection and response to therapy.

  Dustin LB. et al, (2016), Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

• MAIT cells are activated during human viral infections.

  van Wilgenburg B. et al, (2016), Nature communications, 7

• Innate and Adaptive Immune Responses in Chronic HCV infection.

  Dustin LB., (2015), Current drug targets

• Editorial: Recent Advances in HBV and HCV Immunology.

  Dustin LB. and Trehanpati N., (2015), Frontiers in immunology, 6