Research groups
Thomas Perry
BSc (Hons), PhD
Senior Molecular Epidemiologist in the Pathogenesis of OA
- Osteoarthritis (OA) • Molecular Epidemiology • Proteomics • Bioinformatics • Musculoskeletal Imaging • Translational Research
I am a senior molecular epidemiologist and data analyst at the Kennedy Institute of Rheumatology specialising in the integration of large observational cohort datasets with high-dimensional omics data to identify biomarkers, understand treatment response and uncover disease mechanisms in knee osteoarthritis.
My work centres on the STEpUP OA Consortium, where I lead harmonised analyses across more than 1,700 participants from 17 international cohorts, bringing together clinical phenotypes and synovial fluid proteomic data. I oversee study design, statistical modelling, data harmonisation, governance and SOP development, and work closely with academic and industry partners, including GSK and UCB, to support biomarker discovery, validation and translational application.
I also have a strong interest in musculoskeletal imaging, particularly MRI, and in defining structural treatment targets for knee OA clinical trials. Alongside this, I am keen to develop further collaborations in ankle OA and to turn robust epidemiological and bioinformatic analysis into clinically meaningful insight.
Websites
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Code Repository
Research code and resources
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Figshare
Data Repository (STEpUP OA)
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Requests
For STEpUP OA data:
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STEpUP OA: Largest study of knee osteoarthritis synovial fluid
Oxford-led study showing OA has shared core biological pathways and paving the way for more targeted treatments
Recent publications
Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum.
Journal article
Perry TA. et al, (2026), Nat Commun, 17
Biochemical biomarkers of knee osteoarthritis progression: Results from the FNIH biomarkers consortium progress OA study.
Journal article
Collins JE. et al, (2025), Osteoarthr Cartil Open, 7
Peripheral neuronal sensitization and neurovascular remodelling in osteoarthritis pain.
Journal article
Batchelor V. et al, (2025), Nat Rev Rheumatol, 21, 526 - 545