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The COG trial results are published online today - this was a randomised controlled trial to compare gefitinib with placebo in previously treated patients with advanced oesophageal cancer.

The primary publication from the COG trial has been published today, with OCTRU Lead Statistician, Susan Dutton heading up the publication.  The study concluded that the use of gefitinib as a second-line treatment in oesophageal cancer in unselected patients does not improve the overall survival, but has palliative benefits in a subgroup of these difficult-to-treat patients with short life expectancy. Future research should focus on identification of predictive biomarkers to identify this subgroup of benefiting patients.

 

Click here to access the publication 

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