Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

We would like to congratulate Dr Audrey Gérard on her three-year Biotechnology and Biological Sciences Research Council (BBSRC) New Investigator Award. The award will allow Audrey to examine how the behaviour of killer T cells is coordinated to optimise immunity against pathogens and tumour growth.

Dr Audrey Gérard in her lab at the Kennedy Institute.

Killer CD8 T cells attack infected or mutated cells to protect against pathogens and tumour growth. There are many different CD8 T cell clones in the body – only a fraction of these recognise the same target and the amount of protection offered by each clone varies.

Audrey's group uses state-of-the-art imaging approaches to understand how CD8 T cell clones talk to each other during an immune response. Their work will determine how different clones coordinate their activity to rapidly clear infection and establish long-term immunity, while limiting damage to the body's own tissues. This information may guide the development of better vaccines, such as against influenza infection.

"This award is an amazing opportunity for me to tackle this project, which aims to study how CD8 T cells organise themselves as an ecosystem during healthy responses. I believe it will give a different perspective on our understanding of immune response coordination and regulation", said Dr Gérard.

Director of Research at the Kennedy Institute, Professor Michael Dustin, said: "This award recognises Audrey's fundamental work in immunobiology, laying the foundation for future cures."

Audrey joined the Kennedy Institute in 2016 as a Senior Research Fellow funded by the Kennedy Trust for Rheumatology Research.

Funding

BBSRC logo

 

 

 

Similar stories

Small mechanical forces in immune cells measured at unprecedented sensitivity

Kennedy Main Research

Oxford researchers have used advanced microscopy techniques to measure previously unseen forces generated by cells during an immune response; a breakthrough for mechanobiology and future advances in health and disease.

NDORMS researchers awarded for Dupuytren research

Awards Hand Kennedy Main

Three NDORMS researchers have received awards from the International Dupuytren Society, a patient organisation that brings together Dupuytren Disease patient societies from across the world.

Hope for rheumatoid arthritis patients who are non-responsive to anti-TNF

Arthritis Kennedy Main

New research published in The Lancet shows that tocilizumab is a more effective treatment than rituximab for rheumatoid arthritis patients with a poor response to anti-tumour necrosis factor (TNF).

A new study maps the expression of innate immune receptors during the course of arthritis

Arthritis Kennedy Main

The research, which was a collaboration with researchers from Oxford University and Queen Mary University of London and published in Journal of Autoimmunity, looked at changes in receptors known as toll-like receptors (TLRs) in arthritis at different stages of disease.

International Women's Day

Department Main

It’s International Women's Day! This year’s theme is #Choosetochallenge. We’re celebrating some of the amazing women at NDORMS, and asking them what changes they’d like to see in medical sciences over the next 100 years.

Patients and carers invited to join new group helping to shape research and treatment of bones, muscles and joints

Main PPI

Oxford’s newest patient partner group, OPEN ARMS launches today to explore the causes, treatment and care for patients with musculoskeletal conditions. Its first three patient partners explain why they are involved and invite other members of the public to join the team.