Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Dr Stephanie Dakin, an Arthritis Research UK Fellow at NDORMS, has been interviewed by the BBC about her work exploring the treatment of tendon injuries in humans, which builds on her significant experience working with horses.

Dr Stephanie Dakin, an Arthritis Research UK Fellow at NDORMS, is exploring the treatment of tendon injuries in humans building on her significant experience working with horses. She was interviewed this week by the BBC and explains:

Horses are highly evolved to run efficiently. The tendons in their lower limbs function as energy storing springs enabling them to move quickly in an almost passive manner. One disadvantage of this is that these tendons operate very closely to their functional limits, therefore athletic horses are highly prone to developing tendon injuries.

Tendon injuries in horses and humans occur due to a combination of factors including the effects of ageing, repetitive exercise and inflammation. This makes the horse an excellent model of studying tendon pathology in humans. Tendon injuries in both horses and humans are difficult to treat, require prolonged rehabilitation and heal by the formation of scar tissue which is prone to re-injury.

Findings from studying tendon injuries in horses are currently being advanced and translated to help human patients with tendon injuries. It is hoped that the current Arthritis Research UK funded work at the Botnar Research Centre will help to identify new therapies to treat Achilles and rotator cuff tendinopathy in the future. Our goal is to advance this under-researched area of tendon healing so that both human and equine patients can benefit from this research.

The video above has been kindly provided by BBC Oxford to help explain the work that is being done. It can be temporarily viewed at higher quality on the BBC iPlayer service.

Similar stories

Plaster cast or metal pins to treat a broken wrist? The results are in.

An Oxford study published in The BMJ has found the use of metal K-wires (commonly known as ‘pins’) to hold broken wrist bones in place while they heal are no better than a traditional moulded plaster cast.

Professor Chris Buckley has joined the Kennedy Institute as Director of Clinical Research

Moving to the University of Oxford with the Arthritis Therapy Acceleration Programme (A-TAP) will help accelerate the discovery of new treatments for inflammatory diseases.

Behind enemy lines: research finds a new ally in the fight against cardiovascular disease hidden within the vessel wall itself

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters “good” macrophage behaviour within the vessel wall.

More effective treatment found for patients hospitalised with COVID-19 pneumonia

A proof-of-concept trial involving Oxford researchers has identified a drug that may benefit some patients hospitalised with COVID-19 pneumonia.

NDORMS researchers honoured in the Recognition Of Distinction Scheme 2021

Sally Hopewell and John Christianson have been awarded the title of ‘Full Professor’ in the University of Oxford’s Recognition Of Distinction Scheme 2021.

New Oxford-Zeiss Centre of Excellence opens at the University of Oxford

The Kennedy Institute for Rheumatology and the Institute of Developmental and Regenerative Medicine announce the launch of the Oxford-Zeiss Centre of Excellence, providing state-of-the-art imaging technologies to lead future discoveries in global health and disease.