Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Dr Anjali Kusumbe has been awarded an MRC Career Development Award to support her research examining how blood vessels support bone growth and repair.

The prestigious five-year MRC Career Development Award is designed to support talented early stage scientists as they transition to become independent investigators. The award will allow Anjali to pursue an ambitious programme of research aimed at understanding how blood vessels might be targeted to stimulate new bone growth in disease.

Bone is maintained through a delicate balance between breakdown of existing tissue and formation of new bone by cells called osteoblasts. During aging, however, new bone formation becomes less efficient, increasing risk of fractures and other musculoskeletal disorders.

Anjali's previous research as a postdoctoral fellow at the Max Plank Institute, Germany identified a certain type of endothelial cells in blood vessels that create a nurturing environment for bone progenitors. Experimental activation of these endothelial cells could increase bone mass during aging.

Anjali now wants to better understand the signals and cell types that mediate communication between blood vessels and stem/progenitor cells. She hopes this will lead to new strategies to manipulate bone growth and turnover.

Speaking of her award, Anjali said: "It is crucial to improve our understanding of the bone marrow microenvironment in order to identify startegies to treat bone diseases. I'm really excited. Getting an MRC Career Development Award acknowledges the fact that the project is good enough to be financed externally".

Anjali joined the Kennedy Institute in July 2016 supported by funds from the Kennedy Trust for Rheumatology Research.

Similar stories

Immunology preprint reviews launched in Nature Reviews Immunology

Kennedy Main Research

The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.

A more tailored approach to treating psoriatic arthritis

Arthritis Botnar Funding Main

Dr Laura Coates has been awarded £1.8M from the National Institute for Health Research (NIHR) to explore the potential for precision medicine in the choice of biologics to reduce inflammation and pain in psoriatic arthritis.

Motion-capture to help children walk: Oxford team support new gait laboratory in Ethiopia

Main Orthopaedics and trauma

The Research at Oxford on Analysis of Motion (ROAM) team at the University of Oxford have supported CURE Ethiopia Children’s Hospital to develop and open a brand new gait laboratory, the first of its kind in the country and the only other active gait lab on the African continent outside of South Africa.

Professor Eleanor Stride recognised in New Year’s Honours list 2021

Awards Main

Statutory Professor of Biomaterials is awarded Officer of the Order of the British Empire (OBE) for services to Engineering

Drug may boost vaccine responses in older adults

Kennedy Main

A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults

Living reviews launched by Oxford and Cardiff in the wake of COVID-19 research

Kennedy Main Research

In a combined effort to help COVID-19 researchers the University of Oxford and Cardiff University have launched a series of “living reviews” in Oxford University Press’s new open access journal “Oxford Open Immunology”.