Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Dr Anjali Kusumbe has been awarded an MRC Career Development Award to support her research examining how blood vessels support bone growth and repair.

The prestigious five-year MRC Career Development Award is designed to support talented early stage scientists as they transition to become independent investigators. The award will allow Anjali to pursue an ambitious programme of research aimed at understanding how blood vessels might be targeted to stimulate new bone growth in disease.

Bone is maintained through a delicate balance between breakdown of existing tissue and formation of new bone by cells called osteoblasts. During aging, however, new bone formation becomes less efficient, increasing risk of fractures and other musculoskeletal disorders.

Anjali's previous research as a postdoctoral fellow at the Max Plank Institute, Germany identified a certain type of endothelial cells in blood vessels that create a nurturing environment for bone progenitors. Experimental activation of these endothelial cells could increase bone mass during aging.

Anjali now wants to better understand the signals and cell types that mediate communication between blood vessels and stem/progenitor cells. She hopes this will lead to new strategies to manipulate bone growth and turnover.

Speaking of her award, Anjali said: "It is crucial to improve our understanding of the bone marrow microenvironment in order to identify startegies to treat bone diseases. I'm really excited. Getting an MRC Career Development Award acknowledges the fact that the project is good enough to be financed externally".

Anjali joined the Kennedy Institute in July 2016 supported by funds from the Kennedy Trust for Rheumatology Research.

Similar stories

Matthew Costa elected Fellow of Academy of Medical Sciences

Matthew Costa, Professor of Orthopaedic Trauma Surgery at NDORMS, has been elected a Fellow of the Academy of Medical Sciences.

COVID-19’s high blood clot risk

A recent study of patient health records found that around 1 in 100 people with COVID-19 had a venal or arterial thrombosis, with rates higher still among males, and particularly for those hospitalised.

REF 2021 results for medical research in Oxford

Today the UK Funding Bodies have published the outcomes of the recent national research assessment exercise, the Research Excellence Framework (REF) 2021.

Nurses' Day 2022

Today marks Nurses' Day 2022. This year's theme is #BestofNursing, so we chatted to some of our amazing Research Nurses about what the Best of Nursing means to them.

Rethinking pain management after injury

NDORMS researchers are to study whether a pain management treatment using cognitive behavioural therapy will improve recovery for people who have had a major leg injury.

Breakthrough in treatment for Dupuytren’s disease

Injection of the anti-TNF drug adalimumab into Dupuytren’s disease nodules is effective in reducing nodule hardness and nodule size.