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BACKGROUND: New-onset atrial fibrillation (NOAF) is common in patients on an intensive care unit (ICU). Evidence guiding treatments is limited, though recent reports suggest beta blocker (BB) therapy is associated with reduced mortality. METHODS: We conducted a multicentre cohort study of adult patients admitted to 3 ICUs in the UK and 5 ICUs in the USA. We analysed the haemodynamic changes associated with NOAF. We analysed rate control, rhythm control, and hospital mortality associated with common NOAF treatments. We balanced admission and post-NOAF, pre-treatment covariates across treatment groups. RESULTS: NOAF was followed by a systolic blood pressure reduction of 5 mmHg (p 

Original publication




Journal article


J crit care

Publication Date





149 - 156


Arrhythmia, Atrial fibrillation, Critical illness, Intensive care, Management