Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Osteoporosis constitutes a major public health problem through its association with age related fractures. Fracture rates are generally higher in caucasian women than in other populations. Important determinants include estrogen deficiency in women, low body mass index, cigarette smoking, alcohol consumption, poor dietary calcium intake, physical inactivity, certain drugs and illnesses. Thus, modification of physical activity and dietary calcium/vitamin D nutrition should complement high risk approaches. In addition, the recently developed WHO algorithm for evaluation of 10-year absolute risk of fracture provides a means whereby various therapies can be targeted cost-effectively to those at risk. Risk factors, together with bone mineral density (BMD) and biochemical indices of bone turnover, can be utilised to derive absolute risks of fracture and cost-utility thresholds at which treatment is justified. These data will provide the basis for translation into coherent public health strategies aiming to prevent osteoporosis both in individuals and in the general population.

Type

Journal article

Journal

Salud publica de Mexico

Publication Date

01/2009

Volume

51 Suppl 1

Pages

S38 - S45

Addresses

MRC Epidemiology Resource Centre, University of Southampton, UK.

Keywords

Bone and Bones, Humans, Osteoporosis, Bone Resorption, Tomography, X-Ray Computed, Absorptiometry, Photon, Ultrasonography, Risk Assessment, Risk Factors, Bone Density, Female, Fractures, Bone