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OBJECTIVE: to assess whether specialist osteoporosis nurses delivering training to care home staff can reduce fractures and improve the prescription of treatments to reduce fractures versus usual care. DESIGN: pragmatic cluster randomised controlled trial (RCT) with randomisation at the Primary Care Organisation (PCO) level. SETTING: care homes (residential, nursing and EMI) across England and Wales within PCOs. PARTICIPANTS: all 300 PCOs in England and Wales were invited to take part. Of these, 58 agreed to participate and gained ethical approval in time to start the study: 29 clusters were randomised to the intervention group and 29 to the control. INTERVENTION: specialist osteoporosis nurses undertaking short training sessions with care home staff emphase the importance of fracture and fall prevention and train staff on how to identify those residents at high risk of fracture. Residents' risk of fracture and falls was reported to general practitioners (GPs) of patients along with treatment recommendations. OUTCOME MEASURES: primary outcome measures were total fractures over the past 12 months and total hip fractures over past the 12 months. Secondary outcome measures were total home falls, number of residents sustaining a fall, number of residents prescribed bisphosphonates, number of residents prescribed calcium and vitamin D and number of residents wearing hip protectors. All outcomes were measured at the care home level. RESULTS: of the 230 care homes randomised data were collected from 209 of these containing 5,637 residents. There were no differences between the groups in the incidence rate ratios (IRRs) for total fractures (IRR = 0.94 [0.71, 1.26] P = 0.70) or total hip fractures (IRR = 0.86 [0.63, 1.18] P = 0.36). No differences were found between groups for home falls or hip protector use. A significant increase in bisphosphonate prescription was seen in the intervention group over the control group (IRR = 1.50 [1.00, 2.24] P = 0.05). Calcium and vitamin D prescription was significantly increased in the intervention group over the control group (IRR = 1.64 [1.23, 2.18] P<0.01). CONCLUSION: the intervention significantly increased the prescription of bisphosphonates and calcium/vitamin D, but was not associated with a significant effect on the rate of falls or fractures.

Original publication




Journal article


Age ageing

Publication Date





167 - 172


Accident Prevention, Accidental Falls, Aged, Aged, 80 and over, Cluster Analysis, Education, Nursing, Female, Fractures, Bone, Homes for the Aged, Humans, Male, Nursing Homes, Nursing Staff, Professional Competence, Reference Values, Residential Facilities, Risk Factors, Sensitivity and Specificity