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Air pollution is now recognized as an important independent risk factor for cardiovascular morbidity and mortality and may be responsible for up to 3 million premature deaths each year worldwide. The mechanisms underlying the observed effects are poorly understood but are likely to be multifactorial. Here, we review the acute and chronic effects of air pollution exposure on the cardiovascular system and discuss how these effects may explain the observed increases in cardiovascular morbidity and mortality.

Original publication

DOI

10.1111/j.1365-2796.2012.02566.x

Type

Journal article

Journal

J intern med

Publication Date

09/2012

Volume

272

Pages

224 - 239

Keywords

Air Pollution, Blood Flow Velocity, Blood Pressure, Cardiovascular Diseases, Endothelium, Vascular, Environmental Exposure, Fibrinolysis, Heart Rate, Humans, Inflammation, Oxidative Stress, Particulate Matter, Vascular Stiffness, Vasoconstriction