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Neuroimaging makes it possible to study pain processing beyond the peripheral nervous system, at the supraspinal level, in a safe, noninvasive way, without interfering with neurophysiological processes. In recent years, studies using brain imaging methods have contributed to our understanding of the mechanisms responsible for the development and maintenance of chronic pain. Moreover, neuroimaging shows promising results for analgesic drug development and in characterizing different types of pain, bringing us closer to development of mechanism-based diagnoses and treatments for the chronic pain patient.


Journal article


Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Publication Date





755 - 760


Centre for Functional Magnetic Resonance Imaging of Brain, Department of Clinical Neurology, and Nuffield Department of Anaesthetics, University of Oxford, Oxford, England, OX3 9DU, United Kingdom.


Brain, Animals, Humans, Pain, Chronic Disease, Analgesics, Diagnostic Imaging, Drug Discovery