Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Skin infections are a common cause of morbidity in children, particularly in tropical areas. Cultures from such lesions often grow both penicillin-resistant staphylococci and penicillin-sensitive streptococci. In a controlled trial of the treatment of septic skin lesions in 227 paediatric outpatients at Goroka Hospital, sequential analysis of the response to treatment showed that washing plus the intramuscular administration of procaine penicillin was more effective than washing plus placebo (P less than 0.05) after the 25th preference had been decided. When the amount of healing in the two groups was compared, washing plus penicillin was again more effective than washing plus placebo (P less than 0.001; Wilcoxon's rank-sum test). Because it eradicates beta-haemolytic streptococci, penicillin is a safe and effective agent for the treatment of large, multiple, or badly infected skin sores, even in countries such as Australia and Papua New Guinea in which most staphylococci are resistant to penicillin.


Journal article


Med j aust

Publication Date





528 - 530


Bacterial Infections, Child, Clinical Trials as Topic, Humans, Papua New Guinea, Penicillin G Procaine, Penicillin Resistance, Random Allocation, Skin Diseases, Infectious, Staphylococcus