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The properties of three I region associated immunoregulatory factors involved in cell interactions are described. These are antigen specific T helper factor, suppressor factor produced by metabolically active T cells and genetically restricted factor, which is produced by macrophages and is involved in T helper cell induction. The use of these factors to analyse cell interactions is discussed.


Journal article


Adv exp med biol

Publication Date





325 - 338


Animals, Antibody Formation, Genes, MHC Class II, Immunity, Cellular, Immunosuppression, Lymphocyte Cooperation, Lymphocytes, Macrophages, Mice, Peptides