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The recent Juan March Foundation meeting on "Regulation and functional insights in cellular polarity" focused on cellular polarity in yeasts, Dictyostelium, epithelial cells, fibroblasts, and immune cells. The molecular systems covered included membrane rafts, actin and tubulin cytoskeleton, polarized transcription, signaling, and cell-cell adhesion. Across these diverse biological and molecular systems, important general concepts emerged, including new ideas for establishing and maintaining polarity that are likely to be applicable across models and experimental systems.

Original publication

DOI

10.1016/s0092-8674(02)00820-6

Type

Journal article

Journal

Cell

Publication Date

12/07/2002

Volume

110

Pages

13 - 18

Keywords

Actins, Animals, Cell Adhesion, Cell Polarity, Cytoplasm, Humans, Membrane Lipids, Membranes, Microtubules, Signal Transduction, Tubulin, rac GTP-Binding Proteins