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Osteoporosis is a systemic disorder characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. It has a significant impact on public health through the increased morbidity, mortality, and economic costs associated with fractures. Despite the severe medical and socioeconomic consequences of fragility fractures, relatively few adults with fractures are evaluated and/or treated for osteoporosis. In this review, we summarize the existing treatment options and promising new therapies for the prevention and treatment of osteoporosis.

Type

Journal article

Journal

Panminerva medica

Publication Date

01/2014

Volume

56

Pages

273 - 283

Addresses

MRC Lifecourse Epidemiology Unit University of Southampton Southampton General Hospital, Southampton, UK - emd@mrc.soton.ac.uk.

Keywords

Humans, Osteoporosis, Bone Density, Bone Density Conservation Agents