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A number of previous studies have reported a potential risk of malignancy, particularly hematological malignancy, developing in patients receiving a metal-on-metal (MoM) hip replacement. We report a case of malignant lymphoma that arose in a patient who had an MoM hip arthroplasty complicated by development of a pseudotumour. The tumour was a B cell follicular lymphoma that involved lymph nodes and bone. Metal ions are known to have a genotoxic effect on lymphoid cells. Although epidemiological studies have not established that there is an increased risk of lymphoma associated with MoM implants, only a relatively short time period has elapsed since re-introduction of this type of implant and long-term follow-up of patients with MoM implants is indicated.

Original publication

DOI

10.1007/s00256-017-2612-y

Type

Journal article

Journal

Skeletal radiol

Publication Date

06/2017

Volume

46

Pages

831 - 836

Keywords

Hip implant, Lymphoma, Metal on metal, Arthroplasty, Replacement, Hip, Female, Hip Joint, Hip Prosthesis, Humans, Lymphoma, Follicular, Magnetic Resonance Imaging, Metal-on-Metal Joint Prostheses, Middle Aged, Prosthesis Design, Radiography, Ultrasonography