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A 9-year-old boy presented with feeding and behavioural problems and was diagnosed with Autistic Spectrum Disorder and Attention Deficit Hyperactivity Disorder. By age 11 he was becoming increasingly disinhibited and was refusing almost all oral food intake. Believing the cause to be psychogenic, he was placed in an inpatient eating disorder facility. After 3 days of continuous vomiting and minimal intake, he was admitted back to hospital for further investigations. A hypovolaemic hypernatraemia prompted an MRI brain scan, revealing several tumour masses with suprasellar and pituitary involvement. Histological investigation revealed primary, non-malignant germ-cell tumours. The tumours were treated with craniopharyngeal radiotherapy and permanent pituitary hormone replacement.

Original publication

DOI

10.1136/bcr-2012-006870

Type

Journal article

Journal

Bmj case reports

Publication Date

01/2012

Volume

2012

Addresses

Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK.

Keywords

Humans, Germinoma, Brain Neoplasms, Hypopituitarism, Magnetic Resonance Imaging, Attention Deficit Disorder with Hyperactivity, Child Behavior Disorders, Autistic Disorder, Feeding and Eating Disorders of Childhood, Child, Male