Surgical Intervention Trials Unit
Read our latest study
The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial
Read moreWELCOME TO THE SURGICAL INTERVENTION TRIALS UNIT (SITU)
SITU is one of seven Royal College of Surgeons of England specialist trials centres dedicated to evaluating surgical intervention, mainly by generating randomised control trial evidence. We are a multidisciplinary team who provide, guidance, training and support for the development of new surgical trials and future trialists. We draw upon the considerable methodological and practical trials expertise in Oxford including statistical, ethical, health economic, systematic review, clinical network resources and the IDEAL collaboration.
Currently, less than 2% of government funding for medical research goes into surgery
ABOUT
We are a centre of excellence in surgical trials, answering important global surgical questions.
RESEARCH
Read about our research and collaborations in the medical and healthcare research community.
TEAM
Meet our multidisciplinary team of worldwide experts in surgical trials.
EVENTS
Find out more information about our upcoming events.
Latest news
INDICATE Trial Published
8 June 2020
Teya Agnese wins a University of Oxford Apprentice Award
17 March 2020
Work starts on the PRO CURE study!
7 February 2020
An update on the PRO CURE study, which is currently in the process of setting up.
Is surgical repair the best treatment for injuries to the nerves in fingers?
20 November 2019
A new trial, funded by a £1.2 million National Institute of Health Research grant, will explore whether surgery is the best treatment for digital nerve injury.
Selected publications
Instrumental variable methods for a binary outcome were used to informatively address noncompliance in a randomized trial in surgery.
Cook JA. et al, (2018), J clin epidemiol, 96, 126 - 132
Strategies to improve recruitment to randomised trials.
Treweek S. et al, (2018), Cochrane database syst rev, 2
Injection versus Decompression for Carpal Tunnel Syndrome-Pilot trial (INDICATE-P)-protocol for a randomised feasibility study.
Mason W. et al, (2017), Pilot feasibility stud, 3
