Sally Hopewell
MSc, DPhil
Professor of Clinical Trials and Evidence Synthesis
- Theme Lead for Clinical Trials
My key areas of research expertise are in the design, conduct and transparent reporting of randomized trials and systematic reviews. I have published (h-index 74) more than 300 research studies in these areas and have been instrumental in the development of key reporting guidelines including the CONSORT 2025 and SPIRIT 2025 Statements.
In my current role I am involved in leading the design and delivery of clinical trials within the OCTRU portfolio. I am co-chief investigator on several NIHR funded trials in the areas of rehabilitation and musculoskeletal sciences and co-investigator on a number of other NIHR funded trials and evidence syntheses.
Previously, I worked at the Centre for Statistics in Medicine (2007 – 2015) on an MRC-funded programme of research related to CONSORT and the conduct and reporting of clinical trials. I also worked, and continue to collaborate with, the Centre d’Epidemiologie Clinique (2012 – present), University Paris Descartes, on research activities related to the methodology of systematic reviews and randomized trials. Prior to this I worked at the UK Cochrane Centre (2004 – 2012) and with the NHS National Blood Service (2010 – 2012) systematic review programme. In 2005, I was awarded a D.Phil at the University of Oxford on research into the effects of unpublished data in systematic reviews.
I have a particular interest in clinical trial registration, data sharing, transparent reporting of trial protocols, development of core outcome sets, pilot trials and trials of complex interventions. I am a member of the advisory board for Current Controlled Trials, a member of the NIHR Open Research Advisory Board and member of the NIHR Health Technology Assessment Clinical Evaluation and Trials Board (2018-2023). I regularly carry out peer review for high impact medical journals and various funding bodies (e.g. NIHR and Medical Research Council).
I have considerable experience in the teaching and supervision of MSc and DPhil students both at the University of Oxford and Université Paris Descartes; and previously for the London School of Hygiene and Tropical Medicine and Stellenbosch University in South Africa.
Key publications
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Journal article
Hopewell S. et al, (2025), Bmj, 389
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Journal article
Hopewell S. et al, (2025), Jama
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Journal article
Hopewell S. et al, (2025), Nat med
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Journal article
Hopewell S. et al, (2025), Lancet
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Journal article
Hopewell S. et al, (2025), Plos med, 22
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Journal article
Hopewell S. et al, (2025), Bmj, 389
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Journal article
Hopewell S. et al, (2022), Nat med
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Journal article
Chan A-W. et al, (2025), Bmj, 389
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Journal article
Chan A-W. et al, (2025), Plos med, 22
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Journal article
Chan A-W. et al, (2025), Nat med
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Journal article
Hróbjartsson A. et al, (2025), Bmj, 389
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Journal article
Hopewell S. et al, (2021), Lancet, 398, 416 - 428
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Journal article
Orkin AM. et al, (2021), Jama
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Journal article
Howick J. et al, (2020), Plos med, 17
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Journal article
Juszczak E. et al, (2019), Jama, 321, 1610 - 1620
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Journal article
Sterne JAC. et al, (2019), Bmj, 366
Recent publications
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Journal article
Chan A-W. et al, (2025), Nat med
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Journal article
Hróbjartsson A. et al, (2025), Bmj, 389
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Journal article
Chan A-W. et al, (2025), Jama
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Journal article
Chan A-W. et al, (2025), Bmj, 389
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Journal article
Moher D. et al, (2025), J clin epidemiol
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Journal article
Hopewell S. et al, (2025), Nat med
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Journal article
Hopewell S. et al, (2025), Bmj, 389
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Journal article
Hopewell S. et al, (2025), Bmj, 389
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Journal article
Hopewell S. et al, (2025), Lancet
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Journal article
Hopewell S. et al, (2025), Jama
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Journal article
Staniszewska S. et al, (2025), Bmj, 389
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Journal article
Hopewell S. et al, (2025), Plos med, 22
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Journal article
Silva FM. et al, (2025), Am j clin nutr, 121, 882 - 891
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Journal article
Chan A-W. et al, (2025), Plos med, 22
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Journal article
Kahan BC. et al, (2025), Bmj, 388
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Journal article
Rekowski J. et al, (2025), Eclinicalmedicine, 79
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Journal article
Ursino M. et al, (2025), Eclinicalmedicine, 79
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Journal article
Petersen JJ. et al, (2024), Lancet
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Journal article
Welsh A. et al, (2024), Bmc geriatr, 24
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Journal article
Duran M. et al, (2024), J clin epidemiol, 176
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Journal article
Silva FM. et al, (2024), Clin nutr, 43, 1626 - 1635
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Journal article
Clarke M. et al, (2024), J r soc med, 117, 212 - 216
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Journal article
Østengaard L. et al, (2024), Cochrane evidence synthesis and methods, 2
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Journal article
Hopewell S. et al, (2024), Bmj open, 14
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Journal article
Tunn R. et al, (2024), J clin epidemiol, 169
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Journal article
Berner JE. et al, (2024), Rheumatology (oxford)
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Journal article
Smith TO. et al, (2023), Bmj open, 13
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Journal article
Kahan BC. et al, (2023), Jama, 330, 2106 - 2114
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Journal article
Kahan BC. et al, (2023), Jama netw open, 6
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Journal article
Welsh A. et al, (2023), Bmj open, 13
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Journal article
Yap C. et al, (2023), Bmj, 383
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Journal article
Yap C. et al, (2023), Bmj, 383
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Journal article
Sabah SA. et al, (2023), J bone joint surg am, 105, 1611 - 1621
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Journal article
Sabah SA. et al, (2023), Syst rev, 12
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Journal article
Solovyeva O. et al, (2023), Bmc med, 21
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Preprint
Silva FM. et al, (2023)
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Journal article
Speich B. et al, (2023), Jama netw open, 6
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Journal article
Hopewell S. et al, (2023), Nihr open research, 2, 28 - 28
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Journal article
Mellor K. et al, (2023), Pilot feasibility stud, 9
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Journal article
Nicolson PJA. et al, (2023), Pilot feasibility stud, 9
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Journal article
Espinasse A. et al, (2023), Bmj open, 13
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Journal article
Silva F. et al, (2023), Jmir res protoc, 12
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Journal article
Solovyeva O. et al, (2023), Esmo open, 8
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Journal article
Bond C. et al, (2023), Pilot feasibility stud, 9
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Journal article
Mellor K. et al, (2023), Trials, 24
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Journal article
Nejstgaard CH. et al, (2023), J clin epidemiol
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CONSORT 2010 Statement: updated guidelines for reporting parallel group randomized trials
Journal article
Schulz KF. et al, (2023), Japanese pharmacology and therapeutics, 51, 1891 - 1899
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Journal article
Silva FM. et al, (2022), Bmj open, 12
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Journal article
Keene DJ. et al, (2022), Bmj open, 12
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Journal article
Mellor K. et al, (2022), Trials, 23
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Journal article
Siegfried NL. et al, (2022), Trials, 23
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Preprint
Silva F. et al, (2022)
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Journal article
Hopewell S. et al, (2022), Nat med
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Journal article
Hopewell S. et al, (2022), Health technol assess, 25, 159 - 160
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Journal article
Saul H. et al, (2022), Bmj, 378
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Journal article
Speich B. et al, (2022), Trials, 23
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Journal article
Almoajil H. et al, (2022), Dev med child neurol
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Journal article
Schönenberger CM. et al, (2022), J clin epidemiol
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Journal article
Gryaznov D. et al, (2022), Bmj open, 12
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Journal article
Hopewell S. et al, (2022), Nihr open research, 2, 28 - 28
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A COMORBIDITY-TAILORED EXERCISE INTERVENTION FOR PEOPLE AGED 80 YEARS OR OLDER WITH HIP/KNEE OSTEOARTHRITIS: INTERVENTION DEVELOPMENT USING BEHAVIOUR CHANGE THEORY
Conference paper
Nicolson PJ. et al, (2022), Osteoarthritis and cartilage, 30, S197 - S198
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Journal article
Speich B. et al, (2022), Plos med, 19
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Journal article
Mellor K. et al, (2022), Trials, 23
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Journal article
Almoajil H. et al, (2022), Health expect
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Journal article
Almoajil H. et al, (2022), Disability and rehabilitation, 1 - 8
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Journal article
Yap C. et al, (2022), Nat med
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Chapter
Hopewell S. et al, (2022), Principles and Practice of Clinical Trials, 2073 - 2087
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Journal article
Smith T. et al, (2021), Bone jt open, 2, 909 - 920
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Journal article
Speich B. et al, (2021), Jama netw open, 4
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Journal article
Sabah SA. et al, (2021), Bmj open, 11
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Journal article
Lee H. et al, (2021), Jama, 326, 1045 - 1056
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Journal article
Nicolson PJA. et al, (2021), J aging phys act, 1 - 18
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Journal article
Dean BJF. et al, (2021), Rheumatology (oxford), 60, 4094 - 4102
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Journal article
Cook JA. et al, (2021), Pilot feasibility stud, 7
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Journal article
Hopewell S. et al, (2021), Health technol assess, 25, 1 - 158
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Journal article
Hopewell S. et al, (2021), Health technol assess, 25, 1 - 158
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Journal article
Hopewell S. et al, (2021), Lancet, 398, 416 - 428
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Journal article
Cureton L. et al, (2021), Trials, 22
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Randomised study within a trial (SWAT) to evaluate personalised versus standard text
message prompts for increasing trial participant response to postal questionnaires
(PROMPTS)
Journal article
CURETON L. et al, (2021), Trials
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When Factorial Design Randomized Control Trials are no plain sailing
Conference paper
MARIAN I. et al, (2021)
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Challenges in Factorial Design Randomized Control Trials
Conference paper
MARIAN I. et al, (2021)
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Journal article
Mellor K. et al, (2021), Bmj open, 11
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Journal article
Orkin AM. et al, (2021), Jama
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Journal article
Lohner S. et al, (2021), J clin epidemiol
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Journal article
Clarke MJ. et al, (2021), Cochrane database syst rev, 4
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Journal article
Khan MIU. et al, (2021), Pilot feasibility stud, 7
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Journal article
Cohen JF. et al, (2021), Bmj, 372
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Journal article
Speich B. et al, (2021), J clin epidemiol, 131, 70 - 78
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Journal article
Fordham B. et al, (2021), Health technol assess, 25, 1 - 378
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Journal article
Cook JA. et al, (2021), Health technol assess, 25, 1 - 138
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Journal article
Desborough MJR. et al, (2021), Journal of modern oncology, 23, 635 - 636
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Journal article
Dean BJF. et al, (2020), Rheumatology (oxford)
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Journal article
Baldwin M. et al, (2020), Bmj open, 10
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Journal article
Almoajil H. et al, (2020), J child orthop, 14, 562 - 573
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Journal article
Hopewell S. et al, (2020), Br j sports med, 54, 1340 - 1350
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Journal article
Gryaznov D. et al, (2020), Trials, 21
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Journal article
Marian IR. et al, (2020), Trials, 21
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Journal article
Howick J. et al, (2020), Plos med, 17
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Journal article
Cashin AG. et al, (2020), Bmj evid based med
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Journal article
Kasenda B. et al, (2020), Trials, 21
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Journal article
Sherrington C. et al, (2020), Br j sports med, 54, 885 - 891
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Journal article
Estcourt LJ. et al, (2020), Cochrane database syst rev, 7
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Journal article
Estcourt LJ. et al, (2020), Cochrane database syst rev, 7
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Journal article
Khan MI. et al, (2020), Bmj open, 10
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Journal article
Almoajil H. et al, (2020), Dev med child neurol
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Journal article
Dimairo M. et al, (2020), Trials, 21
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Journal article
Abram SGF. et al, (2020), Br j sports med, 54, 652 - 663
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Conference paper
Odutayo A. et al, (2020), Int j epidemiol, 49, 968 - 978
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Journal article
Keene DJ. et al, (2020), Physiotherapy, 107, 252 - 266
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Journal article
Craig RS. et al, (2020), Cochrane database syst rev, 4
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Journal article
Cohen JF. et al, (2020), J clin epidemiol
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Journal article
Estcourt LJ. et al, (2020), Cochrane database syst rev, 4
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Journal article
Speich B. et al, (2020), Bmj open, 10
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Journal article
Almoajil H. et al, (2020), Bmj open, 10
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Journal article
Cashin AG. et al, (2020), Bmc med res methodol, 20
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Journal article
Estcourt LJ. et al, (2020), Cochrane database of systematic reviews
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Design, Analysis and Reporting of Multi-Arm Trials and Strategies to Address Multiple Testing
Journal article
ODUTAYO A. et al, (2019), International journal of epidemiology
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Journal article
Huber J. et al, (2019), Cochrane database syst rev, 11
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Journal article
Chauvin A. et al, (2019), Bmc med, 17
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Journal article
Keene DJ. et al, (2019), Bmj open, 9
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Journal article
Estcourt LJ. et al, (2019), Cochrane database syst rev, 2019
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External Pilot and Feasibility Studies: Past, Present and Future Challenges
Conference paper
Thabane L. et al, (2019), Trials, 20
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What use is an external pilot study?
Conference paper
Eldridge S. et al, (2019), Trials, 20
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Journal article
Riley N. et al, (2019), Bmj open, 9
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Journal article
Sterne JAC. et al, (2019), Bmj, 366
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Journal article
Palmer JS. et al, (2019), Cochrane database syst rev, 7
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Journal article
Palmer JS. et al, (2019), Cochrane database of systematic reviews, 2019
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Journal article
Speich B. et al, (2019), World j surg
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Journal article
Juszczak E. et al, (2019), Jama, 321, 1610 - 1620
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Journal article
Rees JL. et al, (2019), Health technol assess, 23, 1 - 104
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Journal article
Rees JL. et al, (2019), Health technol assess, 23, 1 - 104
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Journal article
Cashin AG. et al, (2019), J clin epidemiol
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Journal article
Wilson HA. et al, (2019), Bmj, 364
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Journal article
Sherrington C. et al, (2019), Cochrane database syst rev, 1
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Journal article
Fordham B. et al, (2018), Bmj open, 8
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Journal article
Greenall G. et al, (2018), Syst rev, 7
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Journal article
Kempf E. et al, (2018), Br j cancer, 119, 1288 - 1296
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Journal article
Estcourt LJ. et al, (2018), Cochrane database syst rev, 9
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Journal article
Deeks JJ. et al, (2018), Cochrane database syst rev, 8
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Journal article
Fortin PM. et al, (2018), Cochrane database syst rev, 8
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Journal article
Grant S. et al, (2018), Trials, 19
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Journal article
Montgomery P. et al, (2018), Trials, 19
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Journal article
Hopewell S. et al, (2018), Cochrane database syst rev, 7
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Journal article
Malouf R. et al, (2018), Cochrane database syst rev, 5
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Journal article
Fortin PM. et al, (2018), Cochrane database syst rev, 5
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Journal article
Estcourt LJ. et al, (2018), Cochrane database syst rev, 4
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Journal article
Hopewell S. et al, (2018), Trials, 19
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Journal article
Cook JA. et al, (2018), Pilot feasibility stud, 4
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Journal article
Craig RS. et al, (2017), Cochrane database of systematic reviews
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Journal article
Shah A. et al, (2017), Bmj open, 7
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Journal article
Abram SGF. et al, (2017), Bmj open, 7
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Journal article
Oakland K. et al, (2017), Endosc int open, 5, E959 - E973
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Journal article
Estcourt LJ. et al, (2017), Cochrane database syst rev, 9
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Journal article
Chauvin A. et al, (2017), Bmj open, 7
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Journal article
Huber J. et al, (2017), Cochrane database syst rev, 2017
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Journal article
Estcourt LJ. et al, (2017), Cochrane database syst rev, 7
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Journal article
Hopewell S. et al, (2017), Bmj open, 7
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Journal article
Desborough MJ. et al, (2017), Cochrane database syst rev, 7
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Journal article
Boutron I. et al, (2017), Ann intern med, 167, 40 - 47
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Journal article
Roy NB. et al, (2017), Cochrane database syst rev, 7
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Journal article
Odutayo A. et al, (2017), Jama cardiol, 2, 782 - 790
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Conference paper
Kempf E. et al, (2017), Journal of clinical oncology, 35, e14023 - e14023
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Journal article
Estcourt LJ. et al, (2017), Cochrane database syst rev, 5
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An assessment of the design and dissemination of phase I clinical trials: where can we improve?
Conference paper
Copsey B. et al, (2017), Trials, 18
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Influence of peer review on the reporting of primary outcome(s) and statistical analyses of randomised trials
Conference paper
Hopewell S. et al, (2017), Trials, 18
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Journal article
Desborough MJR. et al, (2017), Thromb haemost, 117, 889 - 898
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Journal article
Odutayo A. et al, (2017), Jama, 317, 1799 - 1801
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Journal article
Odutayo A. et al, (2017), Lancet gastroenterol hepatol, 2, 354 - 360
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Journal article
Odutayo A. et al, (2017), Bmj, 356
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Journal article
Monk P. et al, (2017), Am j sports med, 45, 965 - 973
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Journal article
Gopalakrishna G. et al, (2017), Diagnostic and prognostic research, 1
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Journal article
Estcourt LJ. et al, (2017), Cochrane database syst rev, 1
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Journal article
Brown J. et al, (2017), Cochrane database syst rev, 1
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Journal article
Estcourt LJ. et al, (2017), Cochrane database syst rev, 1
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Journal article
Estcourt L. et al, (2017), Cochrane database of systematic reviews, 2017
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Journal article
Odutayo A. et al, (2017), J am soc nephrol, 28, 377 - 387
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CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomized trials
Journal article
Schulz KF. et al, (2017), Japanese pharmacology and therapeutics, 45, 479 - 487
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Journal article
Gopalakrishna G. et al, (2017), Diagn progn res, 1
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Methods for Evaluating Medical Tests and Biomarkers : Birmingham, UK. 19–20 July 2016
Journal article
Gopalakrishna G. et al, (2017), Diagnostic and prognostic research, 1
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Journal article
Estcourt LJ. et al, (2017), Cochrane database syst rev, 2017
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Journal article
Pandis N. et al, (2016), Trials, 17
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Overinterpretation and misreporting of prognostic factor studies in medical oncology
Conference paper
Kempf E. et al, (2016), European journal of cancer, 69, S64 - S64
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Journal article
Dinnes J. et al, (2016), J clin epidemiol, 80, 77 - 87
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Journal article
Hopewell S. et al, (2016), Bmc med, 14
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Journal article
Sherrington C. et al, (2016), Cochrane database of systematic reviews, 2016
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Journal article
Desborough M. et al, (2016), Cochrane database syst rev, 10
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Journal article
Eldridge SM. et al, (2016), Bmj, 355
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Journal article
Roy NB. et al, (2016), Cochrane database syst rev, 2016
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Journal article
Estcourt LJ. et al, (2016), Cochrane database syst rev, 2016
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Journal article
Hall DP. et al, (2016), Cochrane database syst rev, 9
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Journal article
Clarke MJ. et al, (2016), Cochrane database syst rev, 9
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Journal article
Odutayo A. et al, (2016), Bmj, 354
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Journal article
Ashraf A. et al, (2016), Cochrane database syst rev, 2016
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Journal article
Fortin PM. et al, (2016), Cochrane database syst rev, 2016
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Journal article
Lazarus C. et al, (2016), J clin epidemiol, 77, 44 - 51
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Journal article
Desborough M. et al, (2016), Cochrane database syst rev
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Journal article
Garner P. et al, (2016), Bmj, 354
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Journal article
Shamseer L. et al, (2016), Trials, 17
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Journal article
Hopewell S. et al, (2016), Cochrane database of systematic reviews, 2016
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Journal article
Malak TT. et al, (2016), Bone joint res, 5, 206 - 214