Research groups
Colleges
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Research Gate
Thomas Hamilton
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Thomas Hamilton
Funding
- National Institute for Health Research Clinical Research Fellowship
- Oxford University Hospitals Trust Innovation Challenge Award
Thomas Hamilton
MBChB, BSc (Hons), MSc, MD, DPhil, MRCS
Academic Clinical Lecturer in Trauma and Orthopaedic Surgery
- Orthopaedic Registrar
Thomas Hamilton graduated first in his year, and second in the UK, in Pharmacology at the University of Edinburgh. He subsequently qualified in medicine and has seven years NHS experience. He is currently completing his doctorate funded by the National Institute for Health Research (NIHR) supervised by Professor David Murray, Professor Hemant Pandit and Dr Stephen Mellon at the Oxford Orthopaedic Engineering Centre.
His principal research interest is optimising patient selection for unicompartmental knee replacement with a particular interest in imaging of the arthritic knee. In addition, building on his pharmacology background, he is passionate about optimising peri-operative recovery in joint replacement patients.
During his D.Phil he has: published the long term outcomes of patients undergoing unicompartmental knee replacement; designed and achieved regulatory approval for OSSKAR (Oxford Stress System for Knee Arthroplasty Radiographs), a medical device for performing stress X-rays of the knee; and developed and validated a radiological decision aid for patient selection for unicompartmental knee replacement.
In addition to these activities Thomas is the lead author of two Cochrane systematic reviews and has experience in statistics, grant writing, ethics submission, trial design and also Patient Public Involvement to prioritise and develop research proposals.
Key publications
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Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain.
Hamilton TW. et al, (2017), Cochrane database syst rev, 2
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A Meta-Analysis on the Use of Gabapentinoids for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty.
Hamilton TW. et al, (2016), J bone joint surg am, 98, 1340 - 1350
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Radiological Decision Aid to determine suitability for medial unicompartmental knee arthroplasty: development and preliminary validation.
Hamilton TW. et al, (2016), Bone joint j, 98-B, 3 - 10
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The clinical outcome of minimally invasive Phase 3 Oxford unicompartmental knee arthroplasty: a 15-year follow-up of 1000 UKAs.
Pandit H. et al, (2015), Bone joint j, 97-B, 1493 - 1500
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Unsatisfactory outcomes following unicompartmental knee arthroplasty in patients with partial thickness cartilage loss: a medium-term follow-up.
Hamilton TW. et al, (2017), Bone joint j, 99-B, 475 - 482
Recent publications
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Pain control post total knee replacement in patients given local infiltrative analgesia combined with adductor canal block compared to either modality alone: a systematic review and meta-analysis
Mott A. et al, (2024), Bmj open, 14, e080555 - e080555
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'The unexpected journey': a qualitative interview study exploring patient and health professionals experiences of participating in the knee arthroplasty versus joint distraction study (KARDS).
Arnold S. et al, (2024), Bmj open, 14
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The outcomes of acute periprosthetic joint infection following unicompartmental knee replacement managed with early debridement, Antibiotics, and implant retention.
Asadollahi S. et al, (2024), Knee, 47, 13 - 20
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Periprosthetic Knee Infection: The Multidisciplinary Oxford Bone Infection Unit Experience
Hamilton TW. et al, (2024), Surgical Management of Knee Arthritis: Advances in Technique and Technology, 187 - 201
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Prosthetic joint infection in the hip and knee
Hamilton T. et al, (2023), Orthopaedics and trauma, 37, 353 - 358