Research groups
Colleges
Websites
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Research Gate
Thomas Hamilton
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Thomas Hamilton
Funding
- National Institute for Health Research Clinical Research Fellowship
- Oxford University Hospitals Trust Innovation Challenge Award
Thomas Hamilton
MBChB, BSc (Hons), MSc, MD, DPhil, MRCS
Academic Clinical Lecturer in Trauma and Orthopaedic Surgery
- Orthopaedic Registrar
Thomas Hamilton graduated first in his year, and second in the UK, in Pharmacology at the University of Edinburgh. He subsequently qualified in medicine and has seven years NHS experience. He is currently completing his doctorate funded by the National Institute for Health Research (NIHR) supervised by Professor David Murray, Professor Hemant Pandit and Dr Stephen Mellon at the Oxford Orthopaedic Engineering Centre.
His principal research interest is optimising patient selection for unicompartmental knee replacement with a particular interest in imaging of the arthritic knee. In addition, building on his pharmacology background, he is passionate about optimising peri-operative recovery in joint replacement patients.
During his D.Phil he has: published the long term outcomes of patients undergoing unicompartmental knee replacement; designed and achieved regulatory approval for OSSKAR (Oxford Stress System for Knee Arthroplasty Radiographs), a medical device for performing stress X-rays of the knee; and developed and validated a radiological decision aid for patient selection for unicompartmental knee replacement.
In addition to these activities Thomas is the lead author of two Cochrane systematic reviews and has experience in statistics, grant writing, ethics submission, trial design and also Patient Public Involvement to prioritise and develop research proposals.
Key publications
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Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain.
Journal article
Hamilton TW. et al, (2017), Cochrane database syst rev, 2
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A Meta-Analysis on the Use of Gabapentinoids for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty.
Journal article
Hamilton TW. et al, (2016), J bone joint surg am, 98, 1340 - 1350
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Radiological Decision Aid to determine suitability for medial unicompartmental knee arthroplasty: development and preliminary validation.
Journal article
Hamilton TW. et al, (2016), Bone joint j, 98-B, 3 - 10
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The clinical outcome of minimally invasive Phase 3 Oxford unicompartmental knee arthroplasty: a 15-year follow-up of 1000 UKAs.
Journal article
Pandit H. et al, (2015), Bone joint j, 97-B, 1493 - 1500
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Unsatisfactory outcomes following unicompartmental knee arthroplasty in patients with partial thickness cartilage loss: a medium-term follow-up.
Journal article
Hamilton TW. et al, (2017), Bone joint j, 99-B, 475 - 482
Recent publications
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Knee arthroplasty compared with joint distraction for osteoarthritis: a phase III randomized controlled trial.
Journal article
Hamilton TW. et al, (2025), Bone jt open, 6, 886 - 893
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Magnetic Resonance Imaging Derived Cartilage Morphological Changes and their Correlation with Patient-Reported Outcome Measures Following Knee Joint Distraction for Osteoarthritis: A 12-Month Cohort Study.
Journal article
Lineham B. et al, (2025), Cartilage
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The definitions and prevalence of nutritional disorders in hip and knee arthroplasty: A systematic review.
Journal article
Little CDJ. et al, (2025), Knee surg sports traumatol arthrosc
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Knee arthroplasty versus knee joint distraction for osteoarthritis: a phase III randomised controlled trial
Conference paper
Hamilton T. et al, (2025), Osteoarthritis and cartilage, 33
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Threaded rods versus arthrodesis nail as a static spacer for two-stage revision total knee arthroplasty.
Journal article
Sina J. et al, (2025), Arch orthop trauma surg, 145