CPinBOSS Study

Paediatric Lower Limb Surgery

PICBONE

ROAM

ROBUST

SPELL

The CELLOS Study

• The PICBone Study

NIHR134125 - Imaging in Paediatric Osteomyelitis (the PICBONE study): a multi-centre cohort study to understand the role of MRI and ultrasound in the diagnosis of acute haematogenous osteomyelitis in children.

•  The SPELL Trial

NIHR135131: Clinical effectiveness of a child-specific dynamic stretching exercise programme, compared to usual care, for ambulant children with spastic cerebral palsy - the SPELL trial.

• The ROBUST Trial

NIHR135150: Clinical effectiveness of an adolescent-specific strengthening programme, compared to usual care, for ambulant adolescents with spastic cerebral palsy - the ROBUST trial.

• The CELLOS Study

Development of a core outcome set for children’s elective lower limb orthopaedic surgery. Funded by the NIHR.

Mr Tim Theologis has been a Consultant Orthopaedic Surgeon in Oxford since 1996 and a Honorary Senior Clinical Lecturer at the University of Oxford since 1999. His clinical and research work focuses on children with cerebral palsy and neuromuscular disorders.

Tim’s previous research has led to the development of the Oxford Foot Model, a biomechanical model for the study of foot motion during walking. This has been adopted internationally by researchers, clinicians and the motion analysis industry as the standard tool for analysis of foot motion in children and adults. The development of the Oxford Foot and Ankle Children's Questionnaire, a validated measure of foot-related disability, was also an important milestone in the understanding of paediatric foot conditions and their impact on lifestyle.

The 'keyhole' or 'minimally-invasive' technique in performing both bony and soft tissue procedures as part of multi-level surgery in children with cerebral palsy has been developed through research at the Oxford Gait Laboratory. It involved surgical techniques which were used in other conditions in children but had not previously been used in the context of surgery in cerebral palsy.

In 2016 Tim led the development of a Research Committee under the auspices of BSCOS, the British Society of Children's Orthopaedic Surgery. He has led the development of research priorities in children’s orthopaedics at national level, including a James Lind Alliance priorities setting project on lower limb surgery in children with orthopaedic conditions.

Since 2017 Tim has dedicated more time in clinical research in paediatric orthopaedics, focusing on cerebral palsy, clinical outcomes and paediatric osteoarticular infection. He completed the CPinBOSS study and is Chief Investigator in 3 other HTA/NIHR funded multi-centre studies, namely PICBone, SPELL and ROBUST. Tim is also supervising the development of a core outcome set in paediatric orthopaedics, the CELLOS study.