Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Everyone knows about a “standard” 2-arm randomised trial, but there are lots of variations on the basic design. Many will be familiar with the more common alternative trial designs, such as cross-over, cluster, multi-arm trials and within-person - these are introduced here. However, beyond these there are many, many alternatives, of which many but by no means all are some sort of adaptive trial.

Below is a not-too-serious list of more unusual/fancier sounding randomised trial designs that I have come across. Inclusion in no way means either I endorse or infer anything good or bad about the design. A more serious point is that the same designs have been presented as new with different labels - and probably will be again.

If you have a name for the list, do send me the reference and I will add.


A non-exhaustive list of less common and fancy Sounding randomised trial designs