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Genetic studies have identified many genetic risks affecting the chance of developing inflammatory diseases or cancers. Only a small minority of these findings have been translated to new knowledge or treatment options, partially due to inter-discipline barriers between Genetics and Immunology.

We would like to overcome these barriers through a unique strategy of integrating datasets from genetic and immunological studies for the goal discovering novel immune regulators and drug targets in human diseases.

Key areas of interests

  1. Identification and validation of novel drug targets in inflammatory arthritis.
  2. Interrogating the immune regulations by the genetic risks shared across common human diseases.
  3. Leveraging genetics to discover common immune pathways key for both autoimmune diseases and cancer.

Recent publications