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Pharmaco-epidemiology is the study of the use and effects of medications in large populations.

We are involved in a number of national and international studies exploring the conditions of use (adherence, compliance, off and on-label use) of a number of licensed drugs for the treatment of musculoskeletal conditions in 'real world' actual practice conditions.

We collaborate with researchers from around the globe to improve our understanding of the safety and effectiveness of new and long-licensed medications and devices for the treatment of arthritis, osteoporosis, and other related conditions. We are also studying both the benefits and the potential risks of the use of such drugs in special subgroups of the population that were under-represented in previous clinical trials.

We have extensive expertise in the analysis and interpretation of large databases including:

  • De-identified electronic medical records from a number of European countries: Clinical Practice Research Datalink from the United Kingdom, SIDIAP from Catalonia, IPCI from the Netherlands, Aarhus Database, Danish National Registries and the OPEN Network, from Denmark to name some
  • Orthopaedic device (also called Joint or Arthroplasty) registries, including the National Joint Registry from England and Wales, and the Catalan Registry of Arthroplasty (RACat, Generalitat de Catalunya) from Catalonia
  • Drug registries, including the British Society of Rheumatology (BSR) Rheumatoid Arthritis Biologics Registry (BSR/BR-RA) and the Danish Biologics Registry (DANBIO)

We have an interest in the development and testing of novel epidemiological methods for the analysis and interpretation of non-randomised studies in the risk/benefit and comparative effectiveness of drugs and devices. 

With this in mind, our overarching aim is the efficient evaluation of health technologies applied to musculoskeletal disorders for a better and safer patient care.

Our Summer School

Clinical studies

Selected publications

Related research themes