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Publications

Peptide gels of fully-defined composition and mechanics for probing cell-cell and cell-matrix interactions in vitro.

Ashworth JC. et al, (2020), Matrix biol, 85-86, 15 - 33

Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling

eyres R. et al, (2019), Nature communications

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

Fagan V. et al, (2019), J med chem, 62, 9008 - 9025

Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

Xiong Y. et al, (2019), J med chem, 62, 8996 - 9007

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.

Christott T. et al, (2019), Slas discov, 24, 133 - 141

Discovery of an MLLT1/3 YEATS Domain Chemical Probe.

Moustakim M. et al, (2018), Angew chem int ed engl, 57, 16302 - 16307

Development of a YEATS-domain chemical probe

Moustakim M. et al, (2018), Abstracts of papers of the american chemical society, 256

Target Identification Using Chemical Probes.

Moustakim M. et al, (2018), 610, 27 - 58

PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression.

Chiang K. et al, (2017), Cell rep, 21, 3498 - 3513

Targeting IL-1 beta-Wnt signalling to prevent breast cancer colonisation in the bone microenvironment

Eyre R. et al, (2017), Clinical & experimental metastasis, 34, 493 - 493

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures.

Morrison E. et al, (2016), J vis exp

Erratum to: Patient-Derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis.

Eyre R. et al, (2016), J mammary gland biol neoplasia, 21

Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis.

Eyre R. et al, (2016), J mammary gland biol neoplasia, 21, 99 - 109

Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.

Maguire SL. et al, (2016), J pathol, 240, 315 - 328

PO-11 - Thrombin and cancer stem-like cells: in vitro support for breast cancer anticoagulation.

Castle J. et al, (2016)

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.

Farnie G. et al, (2015), Oncotarget, 6, 30472 - 30486

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.

Simões BM. et al, (2015), Cell rep, 12, 1968 - 1977

Focal adhesion kinase and Wnt signaling regulate human ductal carcinoma in situ stem cell activity and response to radiotherapy.

Williams KE. et al, (2015), Stem cells, 33, 327 - 341

A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity.

Ablett MP. et al, (2014), Oncotarget, 5, 599 - 612

Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS).

Farnie G. et al, (2014), Cell cycle, 13, 418 - 425

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