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OCTRU runs trials across multiple areas of medicine. Within OCTRU there are five core therapeutic areas of expertise, although trials are also undertaken outside of these areas and groups.

Oncology Clinical Trials Office (OCTO)

Our current portfolio is divided into 3 categories: late phase, early phase and radiotherapy & imaging. Tumours types include; colorectal, oesophageal, melanoma, lung, breast, cervical, haematology, and bone sarcoma, in both adjuvant and advanced disease. The studies assess interventions including radiotherapy, drug combinations and novel imaging techniques.

Trauma and Emergency Care Group

We run a number of clinical trials in orthopaedic trauma and aim to inform best practice in the field, as well as the National Institute for Health and Care Excellence (NICE) guidelines. The Trauma and Emergency Care group is situated at the Kadoorie Critical Care Research Centre located at the John Radcliffe Hospital.

Rehabilitation Research in Oxford (RRIO)

The Centre for Rehabilitation Research in Oxford (RRIO) is a group within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) at University of Oxford. We are leading research into how exercise and physiotherapy can be used to support the rehabilitation of patients with acute musculoskeletal injures such as a fracture or sprain, and patients with chronic conditions, such as rheumatoid arthritis or persistent back pain. We look at how structured physical activity can be offered as an effective method of rehabilitation for patients either alongside, or as an alternative to, standard medication.

Experimental Medicine and Rheumatology

We have experience in trials in rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. We run research from early phase through to large scale phase 3 multi-centre trials.

Surgical Intervention Trials Unit (SITU)

The Surgical Intervention Trials Unit (SITU) is a team of surgical investigators who are providing trial management support, and a training and development hub for surgical trialists within the UK.