Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The term "acute coronary syndromes" (ACS) is used to describe a heterogeneous spectrum of clinical conditions. This includes myocardial infarction, non-ST-elevation myocardial infarction, and unstable angina. These conditions are linked by a similar constellation of signs and symptoms but not necessarily by a common pathophysiology. They are syndromes. Several different hypotheses exist that have attempted to explain the pathological mechanisms that are involved in these conditions, however, it is not clear whether ACS are caused by variations of a single disease process or by several disease processes. The contribution of both vessel wall- and blood-related factors in the pathogenesis of acute coronary syndromes is herein discussed with the guidance of Koch's postulates.

Original publication

DOI

10.1016/j.atherosclerosis.2004.10.022

Type

Journal article

Journal

Atherosclerosis

Publication Date

03/2005

Volume

179

Pages

1 - 15

Addresses

Cytokine Biology of Vessels, Kennedy Institute of Rheumatology & Surgery, Anaesthetic and Intensive Care, Faculty of Medicine, Imperial College, Charing Cross Campus, 1 Aspenlea Road, London W6 8LH, UK.

Keywords

Humans, Coronary Disease, Acute Disease, Coronary Artery Disease