Contact information
daniel.prietoalhambra@ndorms.ox.ac.uk
Mahkameh Mafi
mahkameh.mafi@ndorms.ox.ac.uk
Research groups
Websites
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Athena SWAN
Self assessment-team
- European Health Data & Evidence Network (EHDEN)
- EU ADR Alliance
- International Society of Pharmacoepidemiology (ISPE)
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National Institute for Health Research (NIHR)
Faculty (NIHR Clinician Scientist)
- Observational Health Data Sciences and Informatics (OHDSI)
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SIDIAP Database
International Coordinator
- Erasmus MC University - Medical Informatics
Dani Prieto-Alhambra
MD MSc(Oxf) PhD
Professor of Pharmaco- and Device Epidemiology
- Section Head, Health Data Sciences, Botnar Research Centre
- NIHR Senior Research Fellow
- Fellow of the International Society of Pharmaco-Epidemiology, FISPE
Real World Evidence, Pharmaco-epidemiology, Device Epidemiology
I am an epidemiologist and academic clinician scientist using routinely collected (real world) health data to generate reliable evidence for improved patient care.
Through an NIHR Senior Research Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions and amongst older people with complex health needs.
I lead Pharmaco- and Device Epidemiology research at NDORMS, and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on multiple real world data assets nationally and internationally, and have specialized in network studies using the OMOP Common Data Model.
More recently, I have joined the European Health Data & Evidence Network EHDEN (www.ehden.eu) and the Observational Health Data Sciences and Informatics OHDSI (www.ohdsi.org) in an effort to accelerate and improve the quality of real world evidence internationally.
From February 2022, I am Deputy Director for the European Medicines Agency's Data Analysis and Real World Interrogation Network (DARWIN EU) Coordination Centre, and lead the Development pillar for the generation and/or validation of analytical tools to generate real world evidence for regulatory use.
Key publications
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The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
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Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study.
Cabezas C. et al, (2021), Bmj, 374
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Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis.
Li X. et al, (2022), Bmj, 376
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Characterising the background incidence rates of adverse events of special interest for COVID-19 vaccines across eight countries: a multinational network cohort study
Li X. et al, (2021), The bmj
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Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from five European countries and the US.
Li X. et al, (2022), Bmj, 379
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Renin-angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis.
Morales DR. et al, (2021), Lancet digit health, 3, e98 - e114
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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study.
Lane JCE. et al, (2020), Lancet rheumatol, 2, e698 - e711
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Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study.
Burn E. et al, (2022), Lancet infect dis
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Association of Tramadol vs Codeine Prescriptions With Mortality and Other Adverse Clinical Outcomes-Reply.
Xie J. et al, (2022), Jama, 327, 489 - 490
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Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19.
Xie J. et al, (2022), Jama intern med
Recent publications
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Refinement of post-COVID condition core symptoms, subtypes, determinants, and health impacts: a cohort study integrating real-world data and patient-reported outcomes.
Wang Y. et al, (2024), Ebiomedicine, 111
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Incidence, prevalence, and survival of head and neck cancers in the United Kingdom from 2000-2021
Miquel Dominguez A. et al, (2024)
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Cardinality matching versus propensity score matching for addressing cluster-level residual confounding in implantable medical device and surgical epidemiology: a parametric and plasmode simulation study.
Du M. et al, (2024), Bmc med res methodol, 24
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PDE5 inhibition and Alzheimer’s disease risk: a mendelian randomisation study
Alcalde-Herraiz M. et al, (2024)
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Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes.
Alcalde-Herraiz M. et al, (2024), Nat commun, 15
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Incidence of post-acute COVID-19 symptoms across healthcare settings in seven countries: an international retrospective cohort study using routinely-collected data
Xie J. et al, (2024), Eclinicalmedicine, 77, 102903 - 102903
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Standardised and Reproducible Phenotyping Using Distributed Analytics and Tools in the Data Analysis and Real World Interrogation Network (DARWIN EU).
Dernie F. et al, (2024), Pharmacoepidemiol drug saf, 33
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Evaluation of post-acute COVID-19 health outcomes (ECHOES) in England: The development of national surveillance system for long- term health outcomes following COVID-19
Allen H. et al, (2024)
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Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank
Alcalde-Herraiz M. et al, (2024), Nature communications, 15
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Time Series Methods to Assess the Impact of Regulatory Action: A Study of UK Primary Care and Hospital Data on the Use of Fluoroquinolones.
Guo Y. et al, (2024), Pharmacoepidemiol drug saf, 33