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The latest updates on our research and how it is improving people’s lives.

Vaccine developed to treat osteoarthritic pain

Vaccine developed to treat osteoarthritic pain

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Researchers have developed a vaccine that blocks the effects of the main cause of pain in osteoarthritis (OA) - nerve growth factor (NGF) - in mice.

Genes and height matter for carpal tunnel syndrome

Genes and height matter for carpal tunnel syndrome

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Researchers from the University of Oxford and Estonia have found further evidence that a person’s genetic make-up and height can influence whether they will develop carpal tunnel syndrome (CTS).

Risks of shoulder replacement surgery higher than previously thought

Risks of shoulder replacement surgery higher than previously thought

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Need for further surgery particularly high in younger men and serious complications surprisingly common in older people, say researchers.

Kennedy institute launches oxford centre for microbiome studies

Kennedy Institute launches Oxford Centre for Microbiome Studies

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The Oxford Centre for Microbiome Studies (OCMS) provides unique access to essential technologies to speed up our understanding of how the microbes that inhabit our bodies influence health and disease.

New drug class could offer a targeted safer treatment alternative for patients with rheumatoid arthritis

New drug class could offer a targeted safer treatment alternative for patients with rheumatoid arthritis

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A new treatment targeting tenascin-C could reduce the progression and severity of rheumatoid arthritis (RA) at the very early stages of disease.

You are here home gastroenterology and mucosal immunity study suggests immune system plays key role in survival after pancreatic cancer surgery study suggests immune system plays key role in survival after pancreatic cancer surgery

Study suggests immune system plays key role in survival after pancreatic cancer surgery

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Researchers in Oxford have found that an individual’s immune system – and in particular the presence of T-cells amongst tumour cells – may play an important role in survival after surgery to remove pancreatic cancer.

Pills as good as injections to treat bone and joint infections paper finds

Pills as good as injections to treat bone and joint infections, paper finds

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Pills are just as effective as intravenous (IV) injections in tackling bone infections, a study led by Oxford-based researchers has found.

New cochrane review assesses the benefits and harms of exercise for preventing falls in older people living in the community

New Cochrane review on exercise for prevention of falls in older people

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New research published in the Cochrane Library today provides strong evidence that falls in people over sixty-years old can be prevented by exercise programmes.

Largest ever clinical trial in hip fracture fixation reaches key milestone

Largest-ever clinical trial in hip fracture fixation reaches key milestone

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A randomised controlled trial comparing extracapsular hip fracture fixation devices, conducted by Oxford University and supported by NIHR Oxford Biomedical Research Centre, has reached a key milestone, with the 1000th patient recruited completing their one-year follow-up

Dietary fibre metabolite helps immune system fight invasive bacteria

Dietary fibre metabolite helps immune system fight invasive bacteria

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Macrophages treated with the short-chain fatty acid butyrate – a by-product of dietary fibre breakdown - are better equipped to fight bacteria in the gut, report researchers from the Kennedy Institute and the Translational Gastroenterology Unit. These findings could lead to new strategies to restore gut health in inflammatory bowel disease (IBD).

Oxford scientist set to talk on cancer grand challenge

Professor Fiona Powrie set to take on cancer 'Grand Challenge'

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Oxford scientists are set to benefit from one of the biggest funding grants ever awarded by Cancer Research UK.

Creating a cellular atlas of healthy human joints

Creating a cellular atlas of healthy human joints

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Kennedy researchers, in collaboration with colleagues at the Botnar Research Centre, Oxford, and the Universities of Birmingham and Leeds, have been awarded strategic funding from the Medical Research Council (MRC) to map in detail the different types of cells that make up human joints.

One step closer to targeted therapies for joint inflammation

One step closer to targeted therapies for joint inflammation

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New discoveries on how tissue cells, known as stromal cells contribute to chronic joint inflammation could hold the key to innovative targeted treatments for patients with refractory joint disease.

2018duthie day2019 award for ndorms researchers

‘Duthie Day’ award for NDORMS researcher

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Antony Palmer of NDORMS and Alex Martin were awarded the Kenwright Prizes at this year’s Duthie Day.

First ever epsrc grant to ndorms researcher

Dr Pierre-Alexis Mouthuy awarded EPSRC grant

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Dr Pierre-Alexis Mouthuy has been awarded £1.2m by the Engineering and Physical Sciences Research Council within the Healthcare Technologies theme to develop a humanoid bioreactor for tendon tissue engineering applications.

Ndorms part of large european project on health data and evidence network

NDORMS part of large European project on health data and evidence network

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Professor Daniel Prieto-Alhambra of NDORMS will lead a work package on the generation of evidence from European wide observational data as part of a new Innovative Medicines Initiative project, the European Health Data & Evidence Network (EHDEN).

Improving the reporting of patent landscapes for better decision making

Improving the reporting of patent landscapes for better decision-making

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An international panel of experts led by NDORMS researchers has developed a reporting guideline which supports the reporting quality of patent landscapes, ultimately promoting better informed decision-making in technology development and research direction.

Professor duncan richards to lead clinical therapeutics at oxford

Professor Duncan Richards to lead Clinical Therapeutics at Oxford

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The new Climax Professor of Clinical Therapeutics will join the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the Medical Sciences Division and St Hilda’s College in February 2019 to lead Oxford’s answer to a key global challenge – how to determine quickly which potential new therapies have the properties to become important medicines.

Getting sample sizes right for clinical trials

Getting sample sizes right for clinical trials

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New guidance published yesterday by a team led by NDORMS Associate Professor Jonathan Cook will help researchers recruit the right number of people for clinical trials and answer key research questions.

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